Results 41 to 50 of about 2,491,973 (288)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Inorganic Carbon Acquisition and Photosynthetic Metabolism in Marine Photoautotrophs: A Summary

Plants
The diffusive availability of CO2 for photosynthesis is orders of magnitude lower in water than in air. This, and the low affinity of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) for CO2, implies that most marine photoautotrophs ...
Sven Beer, John Beardall
doaj   +1 more source

Expanding the World of Marine Bacterial and Archaeal Clades

Frontiers in Microbiology, 2016
Determining which microbial taxa are out there, where they live, and what they are doing is a driving approach in marine microbial ecology. The importance of these questions is underlined by concerted, large-scale, and global ocean sampling initiatives ...
Pelin eYilmaz, Pablo eYarza, Josephine Z. Rapp, Josephine Z. Rapp, Frank Oliver eGlöckner, Frank Oliver eGlöckner   +5 more
doaj   +1 more source

The Pitcairn Islands The world's Largest Fully Protected Marine Reserve [PDF]

, 2015
In March 2015, the United Kingdom declared the world's largest fully protected marine reserve in the remote waters surrounding the Pitcairn Islands in the South Pacific Ocean. The designation marks the first time any government has combined creation of a

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Changes in aliphatic hydrocarbon tracer composition during the digestive process of the marine worm Nereis virens. Preliminary results [PDF]

, 1998
In the laboratory, marine worms were fed with a mixture of algae and several aliphatic hydrocarbons for 15 days. By comparing hydrocarbons in food and in faeces, it appeared that the worm's digestive process led to changes in the distribution of the n ...
Atlas, Bauer, Blumer, Forbes, Gardner, Gilbert, Gilbert, Gordon, Karickhoff, Leahy, Lee, Lee, McElroy, McElroy, Myers, Olivier, Plante, Reynoldson, Steinhauer   +18 more
core   +4 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Interdisciplinary Methodology to Extend Technology Readiness Levels in SONAR Simulation from Laboratory Validation to Hydrography Demonstrator

Journal of Marine Science and Engineering, 2019
This paper extends underwater SONAR simulation from laboratory prototype to real-world demonstrator. It presents the interdisciplinary methodology to advance the state of the art from level four to level seven on the technology readiness level (TRL ...
James Riordan, Francis Flannery, Daniel Toal, Matija Rossi, Gerard Dooly   +4 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

A review of the ecological effectiveness of subtidal marine reserves in Central California, Part I: Synopsis of scientific investigations [PDF]

, 2004
Marine reserves, often referred to as no-take MPAs, are defined as areas within which human activities that can result in the removal or alteration of biotic and abiotic components of an ecosystem are prohibited or greatly restricted (NRC 2001 ...
Carr, Mark H., Caselle, Jennifer, Estes, James A., Pomeroy, Caroline, Starr, Richard M., Syms, Craig, VenTresca, David A., Yoklavich, Mary M.   +7 more
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