Results 111 to 120 of about 1,729,318 (198)

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

Passive Metasurface Tweezers for Multi‐Scale Orbital Transport and Trapping on Elastic Plates

open access: yesAdvanced Science, EarlyView.
Passive labyrinthine phase encoding converts single‐channel excitation into localized flexural‐wave vortices with programmable orbital angular momentum. The resulting vortex fields enable cross‐scale particle manipulation, including orbital transport, central confinement, and rotational actuation.
Zeyang Bi   +7 more
wiley   +1 more source

Research on cross-individual fault diagnosis of marine main engines based on adaptive mechanisms

open access: yesZhongguo Jianchuan Yanjiu
ObjectiveTo address the feature drift induced by inter-individual variability in marine main engines and the scarcity of fault data in the target domain, this study leverages digital twin technology and transfer learning to achieve cross-individual fault
Guangxi SUN   +4 more
doaj   +1 more source

Study of Brominated Flame Retardants in Irish Farmed Salmon [PDF]

open access: yes, 2004
The Marine Institute (MI) undertakes monitoring and research relating to contaminants and chemical residues in Irish fisheries products, and works with key agencies such as the Food Safety Authority of Ireland (FSAI) to ensure a high level of consumer ...
Marine Institute
core  

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

open access: yesAdvanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu   +11 more
wiley   +1 more source

Simulation of a diesel engine for testing monitoring systems [PDF]

open access: yes, 2008
This report describes the development of a mathematical model of a mechanically controlled diesel engine for the purpose of implementing an engine simulator.
Benson, Michael John
core  

Polarization Holographic 4D Phenotyping Reveals Nanoplastic Induced Dysfunction in Zooplankton

open access: yesAdvanced Science, EarlyView.
Contaminant‐induced dysfunction in complex aquatic organisms remains difficult to resolve across scales. Polarization Holographic Imaging Microscopy (PHIM) integrates polarization‐sensitive holography with computational volumetric reconstruction for label‐free phenotyping of zooplankton in natural seawater, revealing that nanoplastic stress drives ...
Yuxing Li   +8 more
wiley   +1 more source

Zinc Fingers as Programmable Metalloprotein Scaffolds for Altering Pathogenic Biomolecular Phase Transitions

open access: yesAdvanced Science, EarlyView.
Modular zinc finger (ZF) metalloproteins function as programmable biomolecular scaffolds that modulate pathogenic amyloid assembly. Through direct protein–protein interactions, ZF arrays alter amyloid phase behavior and redirect β‐sheet fibrillization toward nontoxic aggregates.
Seongmin Park   +16 more
wiley   +1 more source

STEADY STATE PERFORMANCES ANALYSIS OF MODERN MARINE TWO-STROKE LOW SPEED DIESEL ENGINE USING MLP NEURAL NETWORK MODEL

open access: yesBrodogradnja, 2016
Compared to the other marine engines for ship propulsion, turbocharged two-stroke low speed diesel engines have advantages due to their high efficiency and reliability.
Ozren Bukovac   +2 more
doaj  

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