Results 221 to 230 of about 197,187 (353)

Universal Regulation of DNA Polymerase via Photocaged Primer Enables Light‐Start Isothermal Amplification on Demand

open access: yesAdvanced Science, EarlyView.
A simple and general photoactivatable approach is developed to regulate DNA polymerase activity, enabling light‐start isothermal amplification on demand. The molecular dynamics simulations reveals that the photocaged primer blocks DNA polymerase activity by inhibiting the conformational change of the polymerase.
Min Qing   +7 more
wiley   +1 more source

Temperature Thresholds Govern Microbial‐Mediated Dissolved Organic Carbon Dynamics in Coastal Ecosystems

open access: yesAdvanced Science, EarlyView.
Coastal dissolved organic carbon (DOC) represents one of the largest reduced carbon pools on Earth, and they are influenced by temperature. Across 7.6–35.9 °C ranges, the microbial‐mediated DOC dynamics is characterized by three temperature thresholds.
Junfu Dong   +12 more
wiley   +1 more source

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