Results 71 to 80 of about 1,113 (212)

Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption

Advanced Science, EarlyView.
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang, Hongliang Li, Shengjie Ma, Sang‐Shin Lee, Lei Wang, Mengyun Hu, Heping Zeng   +6 more
wiley   +1 more source

Developments in exploration and use of marine genetic resources

, 2020
Fil: Kenchington, Ellen.
Blasiak, Robert, Kenchington, Ellen, Arrieta, Jesús M., Bermúdez Monsalve, Jorge Rafael, Calumpong, Hilconida, Changwei, Shao, Chiba, Sanae, Dionisi, Hebe Monica, Garcia Soto, Carlos, Vieira, Helena, Wawrik, Boris   +10 more
openaire   +2 more sources

Marine Genetic Resources, the Nagoya Protocol and the Law of the Sea [PDF]

, 2018
The access and benefit-sharing (ABS) of marine genetic resources (MGRs) within national jurisdiction have received very little interest among scholars and in international discussions. This may seem somewhat surprising given the fact that the vast majority of MGRs with potential for scientific discovery and industrial applications, including deep-sea ...
openaire   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Prokaryotic community structure and key taxa in the Arabian Sea’s oxygen minimum zone

Frontiers in Marine Science
Microbial communities within oxygen minimum zones (OMZs) play crucial roles in the marine biogeochemical cycling. Arabian Sea (AS) has one of the largest OMZs among the global oceans, however, knowledge about the microbial ecology of the AS OMZ remained ...
Ding Li, Ding Li, Ding Li, Liping Wang, Fan Jiang, Fan Jiang, Fan Jiang, Xiang Zeng, Qinzeng Xu, Xuelei Zhang, Qiang Zheng, Qiang Zheng, Zongze Shao   +12 more
doaj   +1 more source

Marine Genetic Resources: An Intellectual Property Perspective

After about 20 years of negotiations in different fora, the United Nations (UN) adopted on 19 June 2023 the Agreement under the United Nations Convention on the Law of the Sea on the conservation and sustainable use of marine biological diversity of areas beyond national jurisdiction (BBNJ Agreement).
Kirchner-Freis, Iris, Kirchner, Andree
openaire   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

A nanobody against CD63 for non-destructive exosome labeling

Biology Direct
Exosomes, also known as small extracellular vesicles, play crucial roles in cancer progression, inflammation, and tissue regeneration, serving as emerging platforms for diagnostics and therapeutic delivery. However, specific and high-affinity binders for
Siyu Chen, Feifan Wang, Cong Chen, Yangjian Cheng, Mingliang Chen, Zengpeng Li, Xixiang Tang   +6 more
doaj   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source