Results 101 to 110 of about 3,091,337 (242)

Imaging‐Based Lensless Polarization‐Sensitive Fluid Stream Analyzer for Automated, Label‐Free, and Cost‐Effective Microplastic Classification

open access: yesAdvanced Intelligent Systems
The presence of microplastics in the environment is of significant concern, yet the exact extent of this pollution remains largely unknown. The ocean is of particular interest as the monitoring of microplastics presents a challenge in that in situ fluid ...
Fraser Montandon, Fred Nicolls
doaj   +1 more source

Bioactive Cembrane Derivatives from the Indian Ocean Soft Coral, Sinularia kavarattiensis

open access: yesMarine Drugs, 2014
Marine organisms and their metabolites represent a unique source of potential pharmaceutical substances. In this study, we examined marine-derived substances for their bioactive properties in a cell-based Chikungunya virus (CHIKV) replicon model and for
Katja-Emilia Lillsunde   +10 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

open access: yesAdvanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang   +6 more
wiley   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

open access: yesAdvanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang   +19 more
wiley   +1 more source

Marine Biotechnology Task Force Report [PDF]

open access: yes, 2017
Marine biotechnology is a rapidly growing area that is recognised, by policy makers and the enterprise sector, as offering significant potential to develop market opportunities for new products and processes by enabling greater utilisation of marine ...
Marine Biotechnology Task
core   +2 more sources

High‐Power Hybrid Nanogenerator With Multi‐Degree‐of‐Freedom Mechanical Coupling for Harvesting Water Wave Energy

open access: yesAdvanced Science, EarlyView.
A high‐power hybrid nanogenerator (HP‐HNG) with multi‐degree‐of‐freedom mechanical coupling is reported, integrating multi‐directional wave energy for output to achieve 1 + 1 > 2 energy harvesting. The HP‐HNG achieves a peak output power of 0.764 W, corresponding to a peak power density of 127.303 W m−3. At a wave frequency of 1 Hz, the HP‐HNG delivers
Shuai Ding   +9 more
wiley   +1 more source

A Development Strategy for Marine Leisure Infrastructure [PDF]

open access: yes, 2001
In July 1999 the Marine Institute published an Investment Strategy for the Water-based Tourism and Leisure Sector in Ireland 2000-2006. The strategy recommended a programme of investment aimed at; (1) the provision of new infrastructure and facilities ...
Marine Institute
core   +1 more source

Review on Optical Detection Technology for Underwater Small Targets

open access: yes水下无人系统学报
The precise detection and identification of small underwater targets, such as micro underwater vehicles and small underwater detectors, constitute important technical support for fields including marine resource development, underwater security early ...
Qingyan CHEN   +3 more
doaj   +1 more source

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

open access: yesAdvanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva   +7 more
wiley   +1 more source

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