Results 31 to 40 of about 13,085 (251)

A Multimodal Approach to Treatment and Management of Rumination Syndrome in a California Sea Lion (Zalophus californianus)

open access: yesAnimals
The management of chronic rumination syndrome in professionally cared-for animals requires a comprehensive and individualized approach. In this case study, a multimodal approach incorporating pharmacological treatment, feeding modifications, and ...
Amber M. Ramos   +8 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Scalable Access to N‑Acylindole Linkages: Enabling the Synthesis of Antitrypanosomal Noncanonical Cyclic Peptides for Chagas Disease

open access: yesAngewandte Chemie, EarlyView.
A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley   +2 more sources

Standardization of Dolphin Cardiac Auscultation and Characterization of Heart Murmurs in Managed and Free-Ranging Bottlenose Dolphins (Tursiops truncatus)

open access: yesFrontiers in Veterinary Science, 2020
Cardiac auscultation is an important, albeit underutilized tool in aquatic animal medicine due to the many challenges associated with in-water examinations.
Barbara K. Linnehan   +17 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Ecological drivers of movement for two sympatric marine predators in the California current large marine ecosystem

open access: yesMovement Ecology
Background An animal’s movement reflects behavioral decisions made to address ecological needs; specifically, that movement will become less directional in regions with high prey availability, indicating foraging behavior.
Ladd M. Irvine   +5 more
doaj   +1 more source

Linkages between human health and ocean health: a participatory climate change vulnerability assessment for marine mammal harvesters [PDF]

open access: yesInternational Journal of Circumpolar Health, 2013
Background. Indigenous residents of Alaska’s Bering Strait Region depend, both culturally and nutritionally, on ice seal and walrus harvests. Currently, climate change and resultant increases in marine industrial development threaten these species
Lily Gadamus
doaj   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch   +13 more
wiley   +1 more source

Dispersal, revisitation, and residency of satellite-tagged blue and fin whales in the Eastern North Pacific Ocean

open access: yesAnimal Biotelemetry
Background We conducted a comparative analysis of movement strategies in blue (Balaenoptera musculus) and fin (B. physalus) whales across the eastern North Pacific (ENP).
Daniel M. Palacios   +6 more
doaj   +1 more source

Capturing foraging and resting behavior using nested multivariate Markov models in an air-breathing marine vertebrate

open access: yesMovement Ecology, 2018
Background Matching animal movement with the behaviors that shape life history requires a rigorous connection between the observed patterns of space use and inferred behavioral states. As animal-borne dataloggers capture a greater diversity and frequency
Ben G. Weinstein   +2 more
doaj   +1 more source

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