Marine-derived myxobacteria of the suborder Nannocystineae: An underexplored source of structurally intriguing and biologically active metabolites [PDF]
Myxobacteria are famous for their ability to produce most intriguing secondary metabolites. Till recently, only terrestrial myxobacteria were in the focus of research.
Antonio Dávila-Céspedes +4 more
doaj +3 more sources
Functional identification of rubber oxygenase (RoxA) in soil and marine myxobacteria. [PDF]
ABSTRACT The rubber oxygenase (RoxA) of Xanthomonas sp. strain 35Y (RoxA Xsp ) is so far the only known extracellular c -type diheme cytochrome that is able to cleave poly( cis -1,4-isoprene).
Birke J +3 more
europepmc +4 more sources
Biogeography and phylogenetic diversity of a cluster of exclusively marine myxobacteria. [PDF]
AbstractMyxobacteria are common in terrestrial habitats and well known for their formation of fruiting bodies and production of secondary metabolites. We studied a cluster of myxobacteria consisting only of sequences of marine origin (marine myxobacteria cluster, MMC) in sediments of the North Sea.
Brinkhoff T +10 more
europepmc +7 more sources
Analysis of the Genome and Metabolome of Marine Myxobacteria Reveals High Potential for Biosynthesis of Novel Specialized Metabolites. [PDF]
AbstractComparative genomic/metabolomic analysis is a powerful tool to disclose the potential of microbes for the biosynthesis of novel specialized metabolites. In the group of marine myxobacteria only a limited number of isolated species and sequenced genomes is so far available.
Amiri Moghaddam J +9 more
europepmc +8 more sources
Enabling Access to Novel Bacterial Biosynthetic Potential From ONT Draft Genomic Data. [PDF]
We demonstrated that a draft genome assembly obtained using long‐read sequencing is enough for the bioprospection of BGCs, and that it allowed us to successfully clone a novel lanthipeptide BGC into a genome engineering‐ready vector, illustrating the capabilities of this strategy for the discovery of novel natural products.
Campos-Magaña MA +2 more
europepmc +2 more sources
Isolation of myxobacteria from the marine environment [PDF]
In an attempt to isolate indigenous marine myxobacteria from coastal samples, we obtained two swarm forming bacteria. Both isolates formed cell aggregates which, at least in one isolate, developed to fruiting body-like structures consisting of a mass of myxospore-like cells.
T, Iizuka +3 more
openaire +3 more sources
Harnessing Gram-negative bacteria for novel anti-Gram-negative antibiotics. [PDF]
In this mini‐review, we highlight prominent examples of novel anti‐Gram negative natural products produced by isolated Gram‐negative bacteria that are currently in pre‐clinical development. Furthermore, we will provide insights into the considerations and strategies behind the discovery of these agents and their putative applications.
Birkelbach J +3 more
europepmc +2 more sources
Phylogeographic separation of marine and soil myxobacteria at high levels of classification [PDF]
Abstract Microorganisms are globally dispersed and are able to proliferate in any habitat that supports their lifestyles, which, however, has not yet been explored in any specific microbial taxon. The social myxobacteria are considered typical soil bacteria because they have been identified in various terrestrial samples, a few in ...
De-Ming, Jiang +5 more
openaire +2 more sources
Stereoselective Syntheses of Cyclic Microsclerodermin Derivatives. [PDF]
Six different cyclic microsclerodermin derivatives are obtained from l‐xylose and d‐arabinose via stereoselective Sakurai allylations and photochemical Arndt‐Eistert homologations. Abstract Starting from l‐xylose and d‐arabinose, six different cyclic microscleroderma derivatives were successfully obtained.
Bauer K, Kazmaier U.
europepmc +2 more sources
A novel xylanase from a myxobacterium triggers a plant immune response in Nicotiana benthamiana. [PDF]
CcXyn, a novel xylanase from the myxobacterium Cystobacter sp. 0969, induces hypersensitive response (HR) and activates defence mechanisms by interacting with the NbRXEGL1 receptor on the cell membrane of Nicotiana benthamiana. Abstract Xylanases derived from fungi, including phytopathogenic and nonpathogenic fungi, are commonly known to trigger plant ...
Zhao Y +9 more
europepmc +2 more sources

