Results 141 to 150 of about 718,059 (342)

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu   +9 more
wiley   +1 more source

Scientific divers quantify first known outbreaks of cold-water coral disease [PDF]

open access: yes, 2009
Coral diseases are widely reported in the tropics but the first incidence of cold-water coral disease was not noted until 2002 when divers recorded an outbreak at 10-28 m depth off Lundy in a NE Atlantic marine protected area.
Hall-Spencer, J, Hiscock, K, Munn, C
core  

EDTA‐Functionalized Nanoscale Metal–Organic Framework for Onco‐Cardiology via Radiochemotherapy Synergy and Spatiotemporally Matched Iron Chelation

open access: yesAdvanced Science, EarlyView.
Doxorubicin (DOX)‐induced cardiotoxicity is a major limitation to its broader clinical application, while cardioprotective interventions often risk reducing the anticancer efficacy of DOX. To address these challenges, this work constructs an EDTA‐functionalized metal–organic framework that enhances tumor therapy and provides efficient cardioprotection ...
Daojing Yuan   +8 more
wiley   +1 more source

Developing marine protected areas

open access: yesEos, Transactions American Geophysical Union, 2006
A draft framework for the development of a national system of marine protected areas (MPA) has been released for public comment by the U.S. National Oceanic and Atmospheric Administration and the U.S. Department of the Interior. Under the proposed framework, an MPA is any area of the marine environment that has been reserved by U.S.
openaire   +1 more source

Review: Insight on Porous Carbon Positive Electrode for Sodium‐Ion Capacitors: Interplay Between Synthesis, Properties, and Performance

open access: yesAdvanced Science, EarlyView.
Sodium ion capacitor (SIC) is currently constrained by the low discharge capacity of commercial activated carbon as positive electrode material. This review provides a holistic summary of research efforts on alternative porous carbon materials for SIC. Image created by the authors with www.biorender.com.
Ademola Adeniji   +2 more
wiley   +1 more source

Marine Protected Area Expansion and Country-Level Age-Standardized Adult Mortality. [PDF]

open access: yesEcohealth, 2023
Haque SS   +6 more
europepmc   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

open access: yesAdvanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo   +19 more
wiley   +1 more source

Status of coral reef fish communities within the Mombasa Marine Protected Area, Kenya, more than a decade after establishment [PDF]

open access: yes, 2012
The abundance, trophic composition and diversity of fish were investigated in the Mombasa Marine Protected Area (MPA) on the Kenya coast over a period of four years (2004-2007) sixteen years after its establishment to determine its effectiveness.
Amiyo, N.   +5 more
core  

Recent Advances in Sustainable Single‐Atom Catalysts from Biomass and Solid Waste: Design, Synthesis and Applications

open access: yesAdvanced Science, EarlyView.
Biomass‐ and solid waste‐derived sustainable single‐atom catalysts (Sus‐SACs) provide a cost‐effective and renewable approach to catalyst design. This review summarizes precursor selection, including AI‐assisted screening, synthesis strategies with emphasis on ultrafast methods, and advanced characterization techniques.
Hongzhe He   +8 more
wiley   +1 more source

Are seafloor habitats influencing the distribution of microplastics in coastal sediments of a Marine Protected Area? [PDF]

open access: yesEnviron Sci Pollut Res Int, 2023
Rios-Fuster B   +6 more
europepmc   +1 more source

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