Results 91 to 100 of about 1,328,349 (302)
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Maximizing the Energy Output of Soft Electrohydraulic Generators
Advanced Science, EarlyView.Many energy resources cannot be viably harvested with electromagnetic generators. This article evaluates the potential of soft electrohydraulic generators as an alternative approach for energy capture. An analytical model charts their operational limits and a rigorous experimental study results in new performance benchmarks with maximum specific energy
Sophie Kirkman +7 more
wiley +1 more source
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
Advanced Science, EarlyView.A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Research Progress on the Impact of Continental Shelf Delimitation on Marine Resources
Redai dili: Continental Shelf Delimitation in Global Ocean Governance: Legal, geopolitical, and Resource Dimensions. Continental shelf delimitation constitutes a central issue in global ocean governance because it directly involves sovereignty claims, access to ...
Ma Renfeng +3 more
doaj +1 more source
Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota
Advanced Science, EarlyView.Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal +25 more
wiley +1 more source
Jurnal Asia Pacific Studies, 2018 Singapore has undertaken coastal reclamation activities since 1976 in the southwest of Singapore's main island bordering the Nipa Island, Riau Archipelago, Indonesia.
Arni Nur Sukma Pertiwi +2 more
doaj
United States, northern border 1878
, 1878 Index map title: Index map, Joint Series. Shows the United States and Canadian border from the summit of the Rocky Mountains to the northwest angle of the Lake of the Woods. Relief shown by hachures and spot heights. Title from second sheet. First sheet
United States Northern Boundary Commission
core
Advanced Science, EarlyView.Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li +11 more
wiley +1 more source