Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
SITREP: The NPS Maritime Defense and Security Research Program Newsletter ; v. 3 (April 2004) [PDF]
This issue highlights the Maritime Domain Protection (MDP) System Architecture Design Process. "Preventing terrorists from exploiting the world's oceans to attack the United States, its forces, its force projection capability, and other interests is a ...
core
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Building Maritime Domain Awareness as an Essential Element of the Global Maritime Fulcrum: Challenges and Prospects for Indonesia\u27s Maritime Security [PDF]
The Global Maritime Fulcrum has been an essential cornerstone of Indonesian foreign and domestic policy for the Joko Widodo administration. It envisions Indonesia as a regional maritime power capable of providing maritime security within its territorial ...
Perwita, A. A. (Anak)
core
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley +1 more source
The release of foulers from protective marine coatings is determined by several interrelated material properties, including the strength of Young's modulus, the flexibility of chain segments, the surface free energy, and the magnitude of hydrodynamic stress.
Johann C. Schaal +2 more
wiley +1 more source
The integrated maritime policy of the European Union in the context of the new oceanic paradigm [PDF]
The lntegrated Maritime Policy (IMP) of the EU is included within the new maritime policy initiatives arisen in the last years both in developed and developing countries.
Rodríguez Mateos, Juan Carlos +1 more
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Increasing maritime situation awareness via trajectory detection, enrichment and recognition of events [PDF]
The research presented in this paper aims to show the deployment and use of advanced technologies towards processing surveillance data for the detection of events, contributing to maritime situation awareness via trajectories’ detection, synopses ...
Alevizos, E. +17 more
core +1 more source

