Results 151 to 160 of about 2,991,056 (299)

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Modification Strategies of Carbon‐Based Electrodes From Structural Regulation to Multifunctional Integration

Advanced Science, EarlyView.
Tracing the evolution from structural regulation to multifunctional integration, this paper systematically analyzes modification strategies for carbon‐based electrodes. It evaluates how element doping, surface functionalization, and composite material design affect the electrode performance, and offers perspectives on future applications and challenges
Yunlei Wang, Shitao Dou, Yifan Wu, Mingguang Wang, Taibin Wu   +4 more
wiley   +1 more source

The Straits of Malacca: Regional powers vis-a-vis littoral states in strategic and security issues and interests [PDF]

, 2010
This paper presents an overview of the strategic and security issues surrounding the Straits of Malacca. It begins by introducing the strategic nature of the Straits of Malacca and piracy threat in the busy sea lane. Subsequently this paper discusses the
Ismail, Siti Zubaidah, Mohd Sani, Mohd Azizuddin   +1 more
core  

Searching for the origins of the myth: 80% human error impact on maritime safety

Reliability Engineering & System Safety, 2021
K. Wróbel
semanticscholar   +1 more source

Defect Engineering Activates Pyrene‐Based Covalent Organic Frameworks for Efficient Photocatalytic Uranium Capture

Advanced Science, EarlyView.
A defect‐engineered pyrene‐based covalent organic framework (TP‐PYTO‐SA) is developed via strategic salicylaldehyde incorporation. This approach simultaneously enhances hydrophilicity and introduces uranyl coordination sites, while optimized defect density significantly improves charge separation.
Weikun Yao, Guanbing Zhou, Tao Liu, Yihui Yuan, Hui Wang, Ning Wang   +5 more
wiley   +1 more source

The integrated application of big data and geospatial analysis in maritime transportation safety management: A comprehensive review

International Journal of Applied Earth Observations and Geoinformation
Maritime transportation plays a pivotal role in global trade, making maritime transportation safety a longstanding priority within the maritime industry.
Xiao Zhou, Zhou Huang, Tian Xia, Xinmin Zhang, Zhixin Duan, Jie Wu, Guoqing Zhou   +6 more
doaj   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu, Haojie Chen, Xiang Li, Jingxin Liu, Yiwen Li, Zhenyi Shi, Shenshen Guo, Qingfeng Du, Aiping Lu, Daogang Guan   +9 more
wiley   +1 more source

Seafarers, seafaring, and occupational identity : 'Jack Tar' and its contemporary uses in Britain c.1815-1914 [PDF]

, 2016
This is a paper about how maritime workers were perceived in the past. In 1968, in a very influential paper, the American historian Jesse Lemisch lamented that ‘Maritime history, as it has been written, has had little to do with the common seaman.’ (1 ...
Gorski, Richard
core  

Methylation‐Induced Permanent Charge Polarization in Covalent Organic Frameworks for Visible Light‐Driven Water Decontamination and Disinfection

Advanced Science, EarlyView.
A targeted in situ methylation strategy is developed to engineer cationic centers in a quinoline‐linked COF (NQ‐COFS1‐Me), creating a strong built‐in electric field, which effectively suppresses excitonic effects and promotes charge separation. The optimized material demonstrates powerful photocatalytic ROS generation for rapid bacterial inactivation ...
Xuewen Peng, Huaji Pang, Niu Feng, Dekang Huang, Chunpeng Jiao, Jingbin Zeng, Yonggang Xiang, Yiping Chen   +7 more
wiley   +1 more source

Research status and prospects of satellite-shore-based integrated network technology for remotely-controlled ships

Zhongguo Jianchuan Yanjiu
The purpose of this work is to optimize the communication architecture for existing remotely-controlled ships to meet the challenges of network connectivity in diverse environments (e.g., ports, deep-sea, and polar regions), aiming to address the issues ...
Xinjue HU, Qi LI, Jialun LIU, Yunlong ZHOU, Nan LIN, Shijie LI   +5 more
doaj   +1 more source