pH‐Driven Two‐Stage Conformational Switching Activates an Acid‐Responsive Chaperone
AchC is an ATP‐independent, pH‐responsive chaperone. AchC functions as a molecular switch, sensing pH changes and undergoing a two‐stage conformational transition: C‐terminal extension (colored in yellow) loosening at mild pH 4.0–5.5 and monomerization at strong acidic pH 3.0.
Soojeong Ham +4 more
wiley +2 more sources
A Multistage Venturi Amplifier for Rapid Inflation of Soft Robots
This work presents the amplifier inflator for soft robotic systems (AIRS), a compact, lightweight, and effective device for rapidly deploying inflatable structures to high pressure. By integrating a check valve with a Venturi‐based air entrainer, AIRS delivers an initial high‐flow output followed by pressurization, supporting fast inflation and ...
Saba Firouznia +4 more
wiley +1 more source
ABSTRACT Maintaining an effective balance between exploration and exploitation is essential during optimization processes, from mathematical functions to more complex problems such as constrained engineering design optimization, particularly when addressing highly nonlinear issues with numerous local optima and strict feasibility requirements.
Enrique Lizárraga +3 more
wiley +1 more source
Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert +31 more
wiley +1 more source
Environmental radiological surveillance in the Baltic Sea: offshore wind farms as platforms for early-warning detection systems. [PDF]
Pająk K +4 more
europepmc +1 more source
Letting losses be lessons: Human-machine cooperation in maritime transport
S. Fan +3 more
semanticscholar +1 more source
Revisiting Animal Reservoirs of Hantavirus and Other Zoonotic Viruses Associated with Cruise Travel: Impact and Prevention. [PDF]
Bonilla-Aldana DK +4 more
europepmc +1 more source
Correction: Hybrid deep learning framework for image restoration in Fso systems affected by log-normal fading. [PDF]
Soliman FA +3 more
europepmc +1 more source
A near real-time carbon accounting framework for the decarbonization of maritime transport
Zhijun Li +4 more
semanticscholar +1 more source
Integrated compositional profiling of ten commercial green coffee lots showed higher mean total phenolic content, DPPH radical‐scavenging activity, β‐carotene, and total phytosterols in Robusta‐labeled lots, whereas Arabica‐labeled lots showed higher mean total tocopherols and total measured fatty acids.
Muyny Chhom +2 more
wiley +1 more source

