Results 41 to 50 of about 185,603,675 (275)
Journal of Neuroinflammation, 2023 Despite extensive astrocyte activation in patients suffering from HIV-associated neurocognitive disorders (HAND), little is known about the contribution of astrocytes to HAND neuropathology.
Jingxian Lun +10 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling +2 more
wiley +1 more source
Age-related memory impairment is associated with disrupted multivariate epigenetic coordination in the hippocampus. [PDF]
PLoS ONE, 2012 Mounting evidence linking epigenetic regulation to memory-related synaptic plasticity raises the possibility that altered chromatin modification dynamics might contribute to age-dependent cognitive decline. Here we show that the coordinated orchestration
James F Castellano +5 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The Selected Writings of Mark Pettinelli [PDF]
The best writing of Mark Pettinelli, about cognitive psychology, cognitive science ...
Pettinelli, Mark
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Österreichische Zeitschrift für Geschichtswissenschaften, 2010 Following Philipp Sarasin, the nation will be analysed as a privileged ‘signifier’ which promises to fix the ever floating chain of ‘signifieds’ and make the world fully understandable. However, as a privileged (or transcendental) signifier cannot be but
Oliver Kühschelm
doaj +1 more source
Marked cognitive decline following COVID-19 infection
Journal of Geriatric Mental Health, 2021 COVID-19 pandemic has influenced humans in many ways. In terms of mental health outcomes, many studies across the globe have shown a high prevalence of anxiety and depression among persons suffering from the acute COVID infection and during the post-COVID infection phase. Additionally, studies have also shown a
Sandeep Grover +3 more
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source