Results 91 to 100 of about 798,456 (298)

Fitting complex ecological point process models with integrated nested Laplace approximation

open access: yes, 2013
Summary 1. We highlight an emerging statistical method, integrated nested Laplace approximation (INLA), which is ideally suited for fitting complex models to many of the rich spatial data sets that ecologists wish to analyse. 2.
Gallego-Fernández, Juan B.   +9 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Detecting Dependence Between Marks and Locations of Marked Point Processes

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 2003
SummaryWe introduce two characteristics for stationary and isotropic marked point proces- ses, E(h) and V(h), and describe their use in investigating mark–point interactions. These quantities are functions of the interpoint distance h and denote the conditional expectation and the conditional variance of a mark respectively, given that there is a ...
Diggle, Peter J.   +2 more
openaire   +3 more sources

Marked Point Process Model for Curvilinear Structures Extraction [PDF]

open access: yes, 2015
International audienceIn this paper, we propose a new marked point process (MPP) model and the associated optimization technique to extract curvilinear structures. Given an image, we compute the intensity variance and rotated gradient magnitude along the
Seong-Gyun Jeong   +5 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

On the Second-Order Characteristics of Marked Point Processes [PDF]

open access: yesBernoulli, 2001
Important data-analytical tools for investigating marked point processes are the second-order characteristics for the locations and the marks. Unnormed second-order characteristics are the mark variogram of Cressie and the mark covariance functions of Cressie and Stoyan.
openaire   +4 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Theatrical Training Marked by Popular Education and Popular Culture:

open access: yesRevista Brasileira de Estudos da Presença, 2023
The article discusses the meanings that young people from peripheral neighborhoods attribute to their theater studying experience marked by popular education and popular culture in an educational institution in Belo Horizonte.
Júlia Camargos
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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