Results 121 to 130 of about 2,046,379 (297)

Smart surgical telementoring system with patch-to-pixel point tracking method

open access: yesEngMedicine
The utilization of surgical telementoring has become increasingly prevalent in enhancing the surgical standards of grassroots hospitals in contemporary times. In the traditional framework of surgical telementoring, remote doctors guide grassroots doctors
Yanwei Qu   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Introdución al análisis de datos mapeados o algunas de las (muchas) cosas que puedo hacer si tengo coordenadas

open access: yesEcosistemas, 2006
An introduction to spatial point pattern analysis or just a few (of many) things that could be done with mapped data. The most frequent analysis of a spatial point pattern is a test of complete spatial randomness.
M. de la Cruz Rot
doaj  

Forgetfulness as an Institutional Policy: The Case of the Palmares Foundation During the Jair Bolsonaro Government (2019-2022)

open access: yesIberoamericana. América Latina - España - Portugal
The Palmares Foundation was created in 1988 in the context of Brazil’s process of re-democratization and the celebration of the one hundred year anniversary of the abolition of slavery in the country.
Amurabi Oliveira
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding position from multiunit activity using a marked point process filter [PDF]

open access: yesBMC Neurosci, 2015
Deng X, Liu D, Kay K, Frank L, Eden U.
europepmc   +1 more source

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