Results 151 to 160 of about 798,456 (298)
Perversión y feminidad: maternidad y masoquismo.
Affectio Societatis, 2015 The concept of perversion in Freud's work is marked by different times to realize a gradual process of complexity whose starting point is the questioning of the evil as purely phenomenological, after which emerges the psychic plane and thus then the ...
Yuliana Andrea Salcedo Escobar
doaj
Finding differentially expressed regions of arbitrary length in quantitative genomic data based on marked point process model. [PDF]
Bioinformatics, 2012 Hatsuda H.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Marked point process model for facial wrinkle detection
, 2014 International audienceWe propose a new model for wrinkle detection in human faces using a marked point process. In order to detect an arbitrary shape of wrinkles, we represent them as a set of line segments, where each segment is characterized by its ...
Jeong, Seong-Gyun +2 more
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Rescaling Marked Point Processes
, 2011 In 1971, Meyer showed how one could use the compensator to rescale a multivariate point process, forming independent Poisson processes with intensity one.
Zaliapin +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Empirical distributions in marked point processes
We study the asymptotic behaviour of the empirical distribution function derived from a stationary marked point process when a convex sampling window is expanding without bounds in all directions. We consider a random field model which assumes that the
Pawlas, Zbynek
core