Results 231 to 240 of about 2,046,379 (297)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Is palpation essential in the digital era of orthotic designing? [PDF]

Front Bioeng Biotechnol
Chhikara K, Morrison S, Wille ML, Herath B, Evans K, Hartley D, Fialho Teixeira MB, Hughes B, Haskell N, Beatson A, Chamorro-Koc M, Little JP, Suresh S.   +12 more
europepmc   +1 more source

An indoor radio mapping dataset combining 3D point clouds and RSSI. [PDF]

Data Brief
Milosheski L, Akiyama K, Bertalanič B, Hribar J, Shinkuma R.   +4 more
europepmc   +1 more source

When Foreign Body Aspiration Is Not the Whole Story: Reconsidering Imaging Escalation in Infants With Apparent Tension Pneumothorax. [PDF]

Clin Case Rep
Awan MA.
europepmc   +1 more source

Understanding coach burnout as a relational process: an autoethnographic case from high-performance trampoline. [PDF]

Front Sports Act Living
Shintani S, Sugita M, Mizushima J.
europepmc   +1 more source

Self-Controlled Automated Strategy for the Synthesis of Gold Nanorods With Fine-Tuned Longitudinal Absorption. [PDF]

Chemistry
Zanoni G, Collini E, Mancin F.
europepmc   +1 more source

Multi-frame pixel intensity consistency-based artifact reduction for photoacoustic computed tomography. [PDF]

Biomed Opt Express
Ma Z, Ouyang B, Li B, Qu Z, Hong X, Yang R, Wang L, Chen J.   +7 more
europepmc   +1 more source

Adoption of a Pediatric Acute Care Cardiology Inpatient Model.

JAMA Netw Open
Gal DB, Georgis JK, Alak-DeBergh S, Pandjaitan I, Yanga De Guzman A, Herrington C, Madsen NL, Kantor PF.   +7 more
europepmc   +1 more source