Results 151 to 160 of about 5,085 (284)
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Directional syncretism without directional rules. [PDF]
Hein J, Murphy A.
europepmc +1 more source
Intrinsic markedness relations in segment structure
This paper is a discussion of the relationship between coronal consonants and theories of segment structure, markedness and underspecification. Much recent research has suggested that the unique, unmarked status of coronals derives solely from an absence
Hamilton, Philip
core
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
The unity of sense and mind: A review of cross-domain mapping. [PDF]
Liu Q, Lupyan G.
europepmc +1 more source
Limitations in Evaluating Machine Learning Models for Imbalanced Binary Outcome Classification in Spine Surgery: A Systematic Review. [PDF]
Ghanem M +6 more
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Quadra Sense: A Fusion of Deep Learning Classifiers for Mitosis Detection in Breast Cancer Histopathology. [PDF]
Alhassan AM, Altmami NI.
europepmc +1 more source
Experimental interpretation of adequate weight-metric combination for dynamic user-based collaborative filtering. [PDF]
Okyay S, Aygun S.
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source

