Results 131 to 140 of about 42,912 (321)

Use of DNA-based genetic markers in plant breeding [PDF]

open access: yes, 2005
Genetic markers have been used since the beginnings of plant breeding, but the concept of linkage and recently the availability of molecular markers have offered new and powerful tools that can help to perform the traditional tasks of selection or that ...
Backes, Gunter
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Construction of RFLP and AFLP Genetic Linkage Maps For Oil Palm (Elaeis Guineensis Jacq.) Using a Deli Dura X Yangambi Pisifera Cross [PDF]

open access: yes, 2006
Conventional oil palm improvement using traditional breeding is a slow and expensive process. If markers linked to a useful trait, such as yield, shell thickness and embryogenesis rate, can be identified, marker-assisted selection (MAS) can be carried ...
Chua, Kia Ling
core  

Validation and implementation of marker-assisted selection (MAS) for the leafing date trait in Persian walnut populations from Iran [PDF]

open access: green, 2023
Mehdi Fallah   +9 more
openalex   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Economic Analysis of Marker-Assisted Selection in Canola [PDF]

open access: yes
Replaced with revised version of poster 07/19/11.Production Economics, Productivity Analysis, Research and Development/Tech Change/Emerging Technologies,
Naseem, Anwar, Singla, Rohit
core   +1 more source

Genetic analysis and qtl mapping of agro-morphological traits in lowland rice (Oryza sativa L.) under drought conditions [PDF]

open access: yes, 2016
The present study was undertaken to evaluate lowland rice genetic variability associated with agro-morphological traits under drought condition. A set of 250 recombinant inbred lines (RILs) from the cross between rice parental cultivarIR64 (sensitive to ...
Audebert, Alain   +6 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Establishment of a broad-spectrum marker for er1/PsMLO1 powdery mildew resistance in pea (Pisum sativum L.) [PDF]

open access: yes, 2018
O oídio, causado pelo fungo ascomycete Erysiphe pisi Syd, é uma das doenças mais importantes que afectam a produção de ervilha (Pisum sativum L.) em Portugal e em países por todo o mundo (Sousa, 1999). Esta doença prospera em climas húmidos temperados
Cardoso, André Filipe Dias Almeida
core  

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