Results 171 to 180 of about 95,506 (252)

Isolation of a Variant of the Felid Herpesvirus 1-Live Attenuated Vaccine Strain F2 from Unvaccinated Cats.

Intervirology
Suga Y, Saito A, Kitamura Y, Kirisawa R.
europepmc   +1 more source

Immune Correlates and Vaccine Immunobridging: Statistical Innovations, Challenges, and Opportunities. [PDF]

J Infect Dis
Carone M, Wolock CJ, Olivas-Martinez A, Rotnitzky A, Gilbert PB.   +4 more
europepmc   +1 more source

A university‐certified course on dossier assessment for regulatory scientists in Africa—Reporting on our 5‐year experience

British Journal of Clinical Pharmacology, EarlyView.
Aim The shortage of trained clinical assessors in African National Regulatory Authorities (NRAs) poses a challenge to effective regulatory decision‐making. Developed in line with the World Health Organization's (WHO) Global Competency Framework (WHO‐GCF), a university‐certified short course, Dossier assessment for clinical assessors in Africa, was ...
Stephanie Leigh, Boitumelo Semete‐Makokotlela, Ivana Škrnjug‐Yudov, David Mukanga, Delese Mimi Darko, Eric Karikari‐Boateng, Peter Stonier, Luther Gwaza, Precious Matsoso, Bernd Rosenkranz, Birka Lehmann, Arnold G. Vulto, John G. Woodland, Shabir Banoo, Frieda Shigwedha, Maphutheho Selikane, Unathi Mabona‐Mgoqi, Asare Yeboah, Ntombi Mthembu, Goonaseelan ( Colin) Pillai   +19 more
wiley   +1 more source

Porcine Parvovirus virus-like particle vaccine induces long-term humoral immunity by recruiting T follicular helper and germinal center B cell responses. [PDF]

Front Immunol
Hao C, Ma Z, Li J, Qiao X, Chen M, Wang J, Li Y, Yao B, Zhang J, Yang Q, Chen P, Jiang D, Ji P.   +12 more
europepmc   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults-A Pilot Study. [PDF]

Aging Cell
Alsaleh G, Ali M, Kayvanjoo AH, Liu F, Moreau T, Bibi S, Luo L, Govender M, Carroll M, Hofer SJ, Tobias E, Magnes C, Kell L, Chung C, Deng Y, Bhandari A, Garner LC, Conrad T, Chen L, Kronsteiner-Dobramysl B, Dunachie S, Spiller OB, Lambe T, Klenerman P, Jones LC, Simon AK.   +25 more
europepmc   +1 more source

More‐than‐gender? Moving beyond gendered expectations of divergent learners in early childhood education

British Educational Research Journal, EarlyView.
Abstract In this paper, we explore how neurodivergent ways of being in early education are often gendered. The intersectionalities of gender and neurodivergence often lead to fixed expectations that perpetuate binary interpretations, pathologisations, missed diagnoses and a lack of curated support.
Ruth Churchill Dower, Hannah Hogarth
wiley   +1 more source

Development of a unified mass cytometry assay integrating activation-induced markers (AIMs) and cytokine profiling for high-throughput assessment of antigen-specific T cell responses. [PDF]

Hum Vaccin Immunother
Wan N, Xue Y, Chen S, Yu H, Ma X, Cheng R, Jiang X, Zhang ZS, Yang W, Li J, Chen Y.   +10 more
europepmc   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

T-cell responses to primary SARS-CoV-2 vaccination in Down syndrome - From childhood to adulthood. [PDF]

Hum Vaccin Immunother
Hensen LCM, Streng BMM, van Wijk F, Nierkens S, Wildenbeest JG, Bont LJ, Delemarre EM, PRIDE study group.   +7 more
europepmc   +1 more source