Results 1 to 10 of about 3,151,999 (148)

The AIFA time-to-reimbursement: a comparison between the last two committees from 2015 to 2020

Global & Regional Health Technology Assessment, 2020
Objective. To compare the time-to-reimbursement of the last two committees of the Italian Medicines Agency (AIFA), respectively appointed in 2015 and in 2018. Methods.
Paola Raimondo, Giorgio Casilli, Martina Isernia, Dario Lidonnici, Roberto Ravasio, Virginia Ronco, Elena Lanati   +6 more
doaj   +1 more source

Price and reimbursement of advanced therapeutic medicinal products in Europe: are assessment and appraisal diverging from expert recommendations?

Journal of Pharmaceutical Policy and Practice, 2021
Background Advanced therapy medicinal products (ATMPs) represent an important cornerstone for innovation in healthcare. However, uncertainty on the value, the high average cost per patient and their one-shot nature has raised a debate on their assessment
Virginia Ronco, Myriam Dilecce, Elena Lanati, Pier Luigi Canonico, Claudio Jommi   +4 more
doaj   +1 more source

Extrapolation of Survival Data Using a Bayesian Approach: A Case Study Leveraging External Data from Cilta-Cel Therapy in Multiple Myeloma

Oncology and Therapy, 2023
Introduction Extrapolating long-term overall survival (OS) from shorter-term clinical trial data is key to health technology assessment in oncology. However, extrapolation using conventional methods is often subject to uncertainty.
Stephen Palmer, Yi Lin, Thomas G. Martin, Sundar Jagannath, Andrzej Jakubowiak, Saad Z. Usmani, Nasuh Buyukkaramikli, Hilary Phelps, Rafal Slowik, Feng Pan, Satish Valluri, Lida Pacaud, Graham Jackson   +12 more
doaj   +1 more source

Early access according to Law 648: a review for the clinician

AboutOpen, 2023
Law 648 has been introduced in Italy in 1996. It allows early access and off label use of novel drugs that fulfill important unmet medical needs. Despite being live for almost twenty years, there are still several areas where the clinician does not have ...
Valentina Drago, Federica Giuffrida
doaj   +1 more source

The Economic impact of Enterosgel® in the hospital treatment of diarrhoeal syndromes associated with different disease conditions

AboutOpen, 2021
Background: Enterosorbents are orally administered materials which pass through the gut where they bind various substances. In a randomized clinical trial, the efficacy and safety of enterosorbent Enterosgel® in the treatment of non-infectious diseases ...
Roberto Ravasio, Paola Raimondo
doaj   +1 more source

Health related quality of life utility weights for economic evaluation through different stages of chronic kidney disease: a systematic literature review

Health and Quality of Life Outcomes, 2020
Background A Task Force from the International Society of Pharmacoeconomics and Outcomes Research (ISPOR) provides recommendations on how to systematically identify and appraise health state utility (HSU) weights for cost-effectiveness analyses.
Jacie T. Cooper, Andrew Lloyd, Juan Jose Garcia Sanchez, Elisabeth Sörstadius, Andrew Briggs, Phil McFarlane   +5 more
doaj   +1 more source

Overall survival of individuals with metastatic cancer in Sweden: a nationwide study

BMC Public Health, 2022
Aims Consistent improvements for overall survival (OS) have been reported for individuals with metastatic cancer. Swedish population-based registers allow national coverage and long follow-up time.
Greta Bütepage, Peter Carlqvist, Johanna Jacob, Asbjørn Toft Hornemann, Simona Vertuani   +4 more
doaj   +1 more source

Economic burden of cancer among patients with surgical resections of the lung, rectum, liver and uterus: results from a US hospital database claims analysis

Health Economics Review, 2017
Objectives To determine hospital resource utilization, associated costs and the risk of complications during hospitalization for four types of surgical resections and to estimate the incremental burden among patients with cancer compared to those without
Iftekhar Kalsekar, Chia-Wen Hsiao, Hang Cheng, Sashi Yadalam, Brian Po-Han Chen, Laura Goldstein, Andrew Yoo   +6 more
doaj   +1 more source

Understanding Diversity of Policies, Functionalities, and Operationalization of Immunization Information Systems and Their Impact: A Targeted Review of the Literature

Vaccines, 2023
The COVID-19 pandemic has focused attention on the use of immunization information systems (IIS) to record and consolidate immunization records from a variety of sources to generate comprehensive patient immunization histories.
Elizabeth A. Donckels, Luke Cunniff, Nina Regenold, Kaitlyn Esselman, Erik Muther, Alexandra Bhatti, Amanda L. Eiden   +6 more
doaj   +1 more source

A comparative study of orphan drug prices in Europe

Journal of Market Access & Health Policy, 2017
Background and Objective: This study assessed price differences by comparing annual treatment costs of similarly available orphan drugs in France, Germany, Italy, Norway, Spain, Sweden, and UK.
Katherine Eve Young, Imen Soussi, Michiel Hemels, Mondher Toumi   +3 more
doaj   +1 more source