Results 231 to 240 of about 3,152,168 (304)
Do European regulatory measures accelerate national market access in Belgium? A retrospective analysis of medicines centrally authorised between 2015 and 2020. [PDF]
Claessens Z +4 more
europepmc +1 more source
Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng +6 more
wiley +1 more source
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas +6 more
wiley +1 more source
Research on the mechanism of leader-follower product sales competition based on market access restrictions and forward contract considerations. [PDF]
Wang L, Cao Z, Li P.
europepmc +1 more source
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo +6 more
wiley +1 more source
Cationic mRNA Lipid Nanoparticles for Ex Vivo NanoCAR‐T Cell Engineering
This study compares charge‑neutral and cationic lipidnanoparticles (LNPs) for ex vivo mRNA delivery to T cells, revealing distinctdependencies on medium composition and T cell activation. Where conventional LNPs benefit from ApoE‐dependent T cell targeting, cationic DOTAP‑modified LNPs mediate unspecific charge‑dependent transfection.
Laure Harinck +9 more
wiley +1 more source
Access in all areas? a round up of developments in market access and health technology assessment: part 4. [PDF]
Beattie A, Treharne C, Ramagopalan SV.
europepmc +1 more source
A MXene‐enhanced electrochemical sensor enables the rapid and direct detection of methamphetamine. Molecular simulations reveal that specific MXene surface functional groups act as key signal amplifiers by facilitating interfacial interactions. The sensor demonstrates high sensitivity and robust performance in complex biological matrices.
Ri Wang +7 more
wiley +1 more source
Optimal Grazing Exclusion Duration to Enhance Soil Carbon Sequestration in Degraded Grasslands
Across China, grazing exclusion reaches the national mean soil organic carbon recovery benchmark sooner in high‐MAP regions (> 500 mm), but recovery is much slower where MAP < 300 mm. Scaling this strategy to 70% of China's degraded grasslands would sequester about 1.52 Pg of soil carbon over 10 years—roughly 17% of annual global fossil‐fuel emissions.
Bin Zhang +9 more
wiley +1 more source

