Results 81 to 90 of about 298,037 (275)

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

Recent vegetational changes on blanket mire at Mynydd Llangatwg, South Wales [PDF]

The Countryside Council for Wales identified that considerable areas of blanket mir~ in South Wales currently support impoverished vegetation as a result of recent anthropogenic influences such as grazing, burning, atmospheric pollution and climate ...
Pearson, Freya R
core   +3 more sources

Unsupervised Representative Feature Selection Algorithm Based on Information Entropy and Relevance Analysis

IEEE Access, 2018
Feature selection plays an important role in preprocessing in pattern recognition and data mining, especially in large scale image, digital text, and biological data.
Yintong Wang
doaj   +1 more source

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

Advanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai, Shuhong Wang, Chenguang Ding, Xenia Kostoulias, Anton P. Le Brun, Hsien‐Yi Hsu, Jhih‐Hang Jiang, Yajun Wang, Richard A. Strugnell, Anton Y. Peleg, Hsin‐Hui Shen   +10 more
wiley   +1 more source

Evaluating Directed Acyclic Graphs with DAGMetrics: Insights from Tuber and Soil Microbiome Data

Agronomy
Understanding and evaluating directed acyclic graphs (DAGs) is crucial for causal discovery, particularly in high-dimensional and small-sample datasets such as microbial abundance data.
Pavel Averin, Ifigeneia Mellidou, Maria Ganopoulou, Aliki Xanthopoulou, Theodoros Moysiadis   +4 more
doaj   +1 more source

A Feature Subset Selection Method Based On High-Dimensional Mutual Information

Entropy, 2011
Feature selection is an important step in building accurate classifiers and provides better understanding of the data sets. In this paper, we propose a feature subset selection method based on high-dimensional mutual information.
Chee Keong Kwoh, Yun Zheng
doaj   +1 more source

Characteristics of Grade IV Glioblastoma Multiforme Markov blanket genes.

, 2013
Characteristics of Grade IV Glioblastoma Multiforme Markov blanket genes.
Changwon Yoo (416678), Brian W. Kunkle (416677), Deodutta Roy (380695)   +2 more
core   +1 more source

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

Advanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma, Huimin Gong, Ran Zhuo, Zaixiao Rao, Yanxi Wan, Mingyang Wang, Zahra Zeinalzadeh, Yuan Gao, Aohan Guan, Xinrun Li, Wanting Chen, Xiliang Wang, Yun Wan, Sihua Zhang, Yuncai Xiao, Qi Huang, Paul R. Langford, Xiangru Wang, Rui Zhou, Rui Luo, Hongbo Zhou, Chengliang Zhu, Hui Jin   +22 more
wiley   +1 more source

Gravity Blanket: on autistic artistic practice

, 2023
My thesis consists of two artistic and one written component. The artistic component is a body of work called Gravity Blanket, which was partly exhibited at Kuvan Kevät graduating masters’ degree show at Exhibition Laboratory (Helsinki, Finland) in May ...
Sandell, Inari
core  

Markov blanket discovery in positive-unlabelled and semi-supervised data [PDF]

, 2015
The importance of Markov blanket discovery algorithms istwofold: as the main building block in constraint-based structure learn-ing of Bayesian network algorithms and as a technique to derive theoptimal set of features in filter feature selection ...
Sechidis, Konstantinos, Brown, Gavin; id_orcid, Konstantinos Sechidis, Gavin Brown   +3 more
core   +1 more source