Results 211 to 220 of about 65,379 (309)

Detecting extirpation: A localized approach to a global problem

PLANTS, PEOPLE, PLANET, EarlyView.
The global biodiversity crisis stems from a cascading series of extirpations driving species toward extinction. Addressing this crisis requires methods for early detection of extinction at local scales, where communities can mobilize conservation efforts.
Andrew D. F. Simon, Antranig Basman, R. Adam Martin, Caitlin Robinson, Quentin Cronk   +4 more
wiley   +1 more source

Modeling Urban Encroachment on the Agricultural Land of the Eastern Nile Delta Using Remote Sensing and a GIS-Based Markov Chain Model [PDF]

, 2018
Kelsee H. Bratley, Eman Ghoneim
openalex   +1 more source

The DNA of Calabi–Yau Hypersurfaces

Fortschritte der Physik, EarlyView.
Abstract Genetic Algorithms are implemented for triangulations of four‐dimensional reflexive polytopes, which induce Calabi–Yau threefold hypersurfaces via Batyrev's construction. These algorithms are shown to efficiently optimize physical observables such as axion decay constants or axion–photon couplings in string theory compactifications.
Nate MacFadden, Andreas Schachner, Elijah Sheridan   +2 more
wiley   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Rare-event simulation with Markov chain Monte Carlo

, 2015
Thorbjörn Gudmundsson
openalex   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

School-based caries prevention and longitudinal trends in untreated decay: an updated analysis with Markov chains. [PDF]

BMC Res Notes, 2020
Ruff RR, Saxena D, Niederman R.
europepmc   +1 more source

Modeling Behavioral Deviations in Adls Using Inverse Reinforcement Learning and Higher-Order Markov Chains

Fateme Akbari, Kamran Sartipi
openalex   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source