Results 251 to 260 of about 771,482 (302)
A Monotone Path Proof of an Extremal Result for Long Markov Chains. [PDF]
Wang J, Chen J.
europepmc +1 more source
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley +1 more source
Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma
ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou +4 more
wiley +1 more source
Impact of Packaging and Recycling Systems on Material Recirculation: A Stage‐Decomposition Model
A system‐level view emerges from decomposing recycling into four stages (participation, collection, sorting and process yield), diagnosing constraints and targeting interventions. Cumulative equivalent uses (CEUs) quantify long‐term retention, revealing marginal improvements at high baselines generate disproportionately larger gains than low‐baseline ...
Diogo Figueirinhas +3 more
wiley +1 more source
ABSTRACT A repairable system operates under a maintenance strategy involving scheduled preventive maintenance (PM) and corrective repair actions following failures. This study develops an exact analytical methodology using Markov chains with discrete states and time to calculate the expected number of failures E[N(t)]$\mathop {\mathbb {E}}[N(t)]$ under
Danilo G. O. Valadares +3 more
wiley +1 more source
A Rank‐Based CUSUM Monitoring Scheme for Time Between Events and Amplitude Data
ABSTRACT Monitoring time between events and amplitude (TBEA) data is critical in many applications, particularly in manufacturing, reliability engineering, and service operations. Yet, most existing TBEA control charts focus on a single quality characteristic and are typically developed under restrictive distributional assumptions.
Muhammad Arslan +5 more
wiley +1 more source
Integrating Image Segmentation and Deep Learning to Improve Radio Frequency Propagation Models
ABSTRACT This paper proposes a multi‐sensor approach to improve radio frequency (RF) propagation models, which play a key role in the rapidly expanding field of connected vehicle technology. Focusing on the 1‐ to 20‐GHz frequency range, which is critical for both satellite‐to‐vehicle and base station‐to‐vehicle communications, our study introduces a ...
Jonathan Israel +2 more
wiley +1 more source
ABSTRACT Energy dependence poses significant risks for economic development, particularly in regions that rely heavily on imported fossil fuels. This paper examines how energy dependence and energy import diversification influence economic development across 27 European Union countries between 2000 and 2022. Using IV‐GMM and panel quantile regressions,
Mehmet Pinar
wiley +1 more source

