Results 51 to 60 of about 810,691 (251)
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source
PSO-Markov residual correction method based on Verhulst-Fourier prediction model
Systems Science & Control Engineering, 2021 Macroeconomic predicting is a research hotspot in the field of predicting. The accuracy of predicting often directly affects the rationality of decision-making, especially for defense expenditure predicting.
Tong Niu +5 more
doaj +1 more source
Multi-type relational clustering approaches : current state-of-the-art and new directions [PDF]
, 2008 The proliferation of multi-type relational datasets in a number of important real-world applications and the limitations resulting from the transformation of such datasets to fit propositional data mining approaches have led to the emergence of the ...
Anand, Sarabjot Singh, Li, Tao
core +1 more source
Clustering in Block Markov Chains [PDF]
, 2020 This paper considers cluster detection in Block Markov Chains (BMCs). These Markov chains are characterized by a block structure in their transition matrix.
Sanders, Jaron +9 more
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Advanced Science, EarlyView.We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka +10 more
wiley +1 more source
Advanced Science, EarlyView.MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge +13 more
wiley +1 more source
Advanced Science, EarlyView.Subcellular spatial transcriptomics enables high‐resolution mapping of gene expression within tissues, but accurate cell segmentation is essential for assigning transcripts to individual cells. We present SpaCut, a deep learning framework that integrates transcriptomic features with nucleus‐guided morphological information to precisely delineate cell ...
Yongheng Li, Fangfang Zhu, Wenwen Min
wiley +1 more source
ISPRS International Journal of Geo-Information, 2019 With the accelerated urbanization process, cities are suffering from extremely heavy rain and urban storm water logging disasters in recent years. To provide reliable and effective information for urban management and emergency decision-making, the ...
Yanmei Wang +4 more
doaj +1 more source
A Text Clustering Algorithms Based on Hidden Markov Model
, 2011 Based on the probability model of clustering algorithm constructs a model for each cluster, calculate probability of every text falls in different models to decide text belongs to which cluster, conveniently in global Angle represents abstract structure ...
Wei Li, Mei An Li
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ReLink: Reliable Deep Learning for Microscopic Motion Tracking
Advanced Science, EarlyView.ReLink enables reliable trajectory linking in single‐particle tracking by integrating physics‐informed motion statistics with confidence‐based adaptive filtering. Across diverse simulated and experimental conditions, ReLink robustly reconstructs trajectories and preserves the fidelity of downstream analyses, enabling accurate characterization of ...
Yuan Jiang +7 more
wiley +1 more source