Results 141 to 150 of about 4,564 (243)

Carbon Emissions From Different Functional Zones of Construction Land in the Yellow River Basin Based on Nighttime Light Data and POI Data

open access: yesLand Degradation &Development, Volume 37, Issue 14, Page 10387-10404, 30 August 2026.
ABSTRACT The Yellow River Basin is a critical region for ecological conservation and sustainable development in China. It also serves as a core area for carbon emissions across various functional zones of construction land. Accurately understanding carbon emissions from various types of construction land in the Yellow River Basin is crucial for China ...
Xi Chen   +7 more
wiley   +1 more source

BEAST X for Bayesian phylogenetic, phylogeographic and phylodynamic inference. [PDF]

open access: yesNat Methods
Baele G   +10 more
europepmc   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

open access: yesAdvanced Science, Volume 13, Issue 44, 7 August 2026.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott   +5 more
wiley   +1 more source

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

open access: yesAdvanced Science, Volume 13, Issue 44, 7 August 2026.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang   +8 more
wiley   +1 more source

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li   +10 more
wiley   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

open access: yesAdvanced Intelligent Discovery, Volume 2, Issue 4, August 2026.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu   +4 more
wiley   +1 more source

Advanced Experiment Design Strategies for Drug Development

open access: yesAdvanced Intelligent Discovery, Volume 2, Issue 4, August 2026.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang   +3 more
wiley   +1 more source

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