Results 71 to 80 of about 15,456,603 (251)
Evolutionary morphology of the haplorhine hamate
The Anatomical Record, EarlyView.Abstract Primates adopt a variety of hand postures during an impressive diversity of locomotor and manipulative behaviors. Morphological research has found that elements of the hand skeleton, such as the hamate, hold key information for inferring hand use and locomotor kinematics in extinct species.
Laura E. Hunter +4 more
wiley +1 more source
Option pricing using hidden Markov models [PDF]
, 2006 Includes bibliographical references (leaves 144-149).This work will present an option pricing model that accommodates parameters that vary over time, whilst still retaining a closed-form expression for option prices: the Hidden Markov Option Pricing ...
Anderson, Michael
core +1 more source
Markov-Switching Model Selection Using Kullback-Leibler Divergence [PDF]
In Markov-switching regression models, we use Kullback-Leibler (KL) divergence between the true and candidate models to select the number of states and variables simultaneously.
Tsai, Chih-Ling +2 more
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British Journal of Clinical Pharmacology, EarlyView.Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić +4 more
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Geo-spatial Information ScienceLocation-Based Services (LBS) have become integral to contemporary urban life, with Global Navigation Satellite System (GNSS) modules in smart devices serving as the primary geospatial data source.
Jingxian Wang +5 more
doaj +1 more source
rEMM: Extensible Markov Model for Data Stream Clustering in R [PDF]
Clustering streams of continuously arriving data has become an important application of data mining in recent years and efficient algorithms have been proposed by several researchers. However, clustering alone neglects the fact that data in a data stream
Michael Hahsler, Margaret H. Dunham
core
British Journal of Clinical Pharmacology, EarlyView.ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said +13 more
wiley +1 more source
Trajectory Learning Using HMM: Towards Surgical Robotics Implementation
SensorsAutonomy represents one of the most promising directions in the future development of surgical robotics, and Learning from Demonstration (LfD) is a key methodology for advancing technologies in this field.
Juliana Manrique-Cordoba +3 more
doaj +1 more source
Forecasting the Turns of German Business Cycle: Dynamic Bi-factor Model with Markov Switching [PDF]
In this paper a dynamic bi-factor model with Markov switching is proposed to measure and predict turning points of the German business cycle. It estimates simultaneously the composite leading indicator (CLI) and composite coincident indicator (CCI ...
Konstantin A. Kholodilin
core