Results 141 to 150 of about 10,800,365 (307)
Arthritis &Rheumatology, EarlyView.Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen +23 more
wiley +1 more source
A Multi-stage Representation of Cell Proliferation as a Markov Process. [PDF]
Bull Math Biol, 2017 Yates CA, Ford MJ, Mort RL.
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić +4 more
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said +13 more
wiley +1 more source
The research on the strong Markov property
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2011 Let $X(t, omega) = {x_t(omega): t geq 0} be a Markov process defined on a probability space $(Omega,mathcal{F}, P)$ and valued in a measurable space (E; mathcal{E} ).
Huang Yonghui, Tang Rong
doaj
Dynamic chromatin accessibility modeled by Markov process of randomly-moving molecules in the 3D genome. [PDF]
Nucleic Acids Res, 2017 Wang Y, Fan C, Zheng Y, Li C.
europepmc +1 more source
Beveridge-Nelson Decomposition with Markov Switching [PDF]
This paper considers Beveridge-Nelson decomposition in a context where the permanent and transitory components both follow a Markov switching process.
Heather Anderson +2 more
core
Economic evaluations of antiobesity medications: A systematic literature review
British Journal of Clinical Pharmacology, EarlyView.The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković +5 more
wiley +1 more source