Results 171 to 180 of about 557,874 (331)

Prediction of neutrophil nadir and recovery following paediatric haematopoietic cell transplantation with busulfan conditioning

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims In haematopoietic cell transplantation (HCT), neutropenia resulting from myelosuppression is an expected endpoint following busulfan‐based conditioning. However, if prolonged, neutropenia can lead to complications like serious infection and death.
Beth Apsel Winger   +6 more
wiley   +1 more source

Reinforcement Learning for Robust Dynamic Metabolic Control

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Dynamic metabolic control allows key metabolic fluxes to be modulated in real time, enhancing bioprocess flexibility and expanding available optimization degrees of freedom. This is achieved, for example, via targeted modulation of metabolic enzyme expression.
Sebastián Espinel‐Ríos   +2 more
wiley   +1 more source

A comparison of time-homogeneous Markov chain and Markov process multi-state models. [PDF]

open access: yesCommun Stat Case Stud Data Anal Appl, 2016
Wan L, Lou W, Abner E, Kryscio RJ.
europepmc   +1 more source

ThiF‐Like Enzyme Chemistry in Primary and Secondary Metabolism

open access: yesChemBioChem, EarlyView.
ThiF‐like enzymes are a widespread protein family found in disparate biosynthetic pathways. They are unified by their use of an NTP to modify a carboxylate, generating an activated species prone to nucleophilic addition. This common intermediate is then targeted by diverse nucleophiles, including persulfide or amino acid side chains, to yield a variety
Keelie S. Butler   +2 more
wiley   +1 more source

Real‐World Outcome of Coronary Orbital Atherectomy in Diabetic Versus Non‐Diabetic Patients: A Single‐Center Experience

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background and Aims Clinical trial research on the safety and efficacy of coronary orbital atherectomy (OA) in diabetics compared to non‐diabetics is limited. This single‐center study aimed to perform a diabetic comparative analysis using real‐world data.
Benjamin Klein   +9 more
wiley   +1 more source

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