Results 131 to 140 of about 14,010 (266)

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity

open access: yesBrain Pathology, EarlyView.
How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova   +11 more
wiley   +1 more source

Finite-Time Annular Domain Stability and Stabilization of Regime-Switching Jump Diffusion System

open access: yesIEEE Access
In this paper, the finite-time annular domain stability and stabilization of regime-switching jump diffusion system are discussed. With the help of explicit solution of multi-dimensional regime-switching jump diffusion system, we give the sufficient and ...
Ran Ni, Gui-Hua Zhao
doaj   +1 more source

The impact of coal combustion, nitrous oxide emissions, and traffic emissions on COVID-19 cases: a Markov-switching approach. [PDF]

open access: yesEnviron Sci Pollut Res Int, 2021
Anser MK   +5 more
europepmc   +1 more source

Decoding functional specialization in G protein‐coupled receptors (GPCRs) through evolution‐guided residue profiling

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are integral membrane proteins that mediate physiological processes by enabling cells to detect and respond to diverse stimuli. Although many subfamily‐specific functional hotspots have been described, the family‐wide determinants of common and subfamily‐specific functions remain incomplete ...
Berkay Selçuk   +3 more
wiley   +1 more source

Edge‐preserving noise for diffusion models

open access: yesComputer Graphics Forum, EarlyView.
Abstract Classical diffusion models typically rely on isotropic Gaussian noise, treating all regions uniformly and overlooking structural information important for high‐quality generation. We introduce an edge‐preserving diffusion process that generalizes isotropic models via a hybrid noise scheme with an edge‐aware scheduler that smoothly transitions ...
Jente Vandersanden   +3 more
wiley   +1 more source

Survey on Compositional 3D Indoor Scene Generation

open access: yesComputer Graphics Forum, EarlyView.
This survey provides a comprehensive overview of compositional 3D indoor scene generation, introducing a unified framework for categorizing existing methods, comparing their strengths and limitations and identifying key challenges and future research directions.
H. I. I. Tam   +7 more
wiley   +1 more source

Omnipod 5 Delivers Superior Economic Value Compared to Multiple Daily Injections: A Cost‐Effectiveness Analysis in Adults With T1D From a Payer Perspective in Sweden

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Analyse the cost‐effectiveness of the Omnipod 5 automated insulin delivery system versus multiple daily injections (MDI) with continuous glucose monitoring for type 1 diabetes among adults in Sweden. Methods Cost‐effectiveness was analysed with the IQVIA Core Diabetes Model (version 10.0) taking the perspective of the payer in Sweden ...
Johan Jendle   +5 more
wiley   +1 more source

Economic Burden of Chronic Lymphocytic Leukaemia in Australia

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background The treatment landscape for chronic lymphocytic leukaemia (CLL) has transformed over the past decade. This study aimed to estimate the healthcare costs and health burden associated with CLL in Australia. Methods A Markov model was developed to simulate the lifetime healthcare costs and health outcomes associated with CLL in ...
Lan Gao   +4 more
wiley   +1 more source

Paving the way for incumbents' digital transformation. A review and research agenda

open access: yesEuropean Management Review, EarlyView.
Abstract Digital transformation is reshaping the competitive landscape by forcing incumbent firms to rethink their strategies, organizational structures, and business models. While a substantial body of literature has explored digital transformation in specific sectors, focusing on various factors and organizational mechanisms, there remains a lack of ...
Anna Bastone   +3 more
wiley   +1 more source

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