Results 61 to 70 of about 46,147 (264)

Histamine release from intestinal mast cells induced by staphylococcal enterotoxin A (SEA) evokes vomiting reflex in common marmoset

PLoS Pathogens, 2019
Staphylococcal enterotoxins (SEs) produced by Staphylococcus aureus are known as causative agents of emetic food poisoning. We previously demonstrated that SEA binds with submucosal mast cells and evokes mast cell degranulation in a small emetic house ...
H. Ono, Shouhei Hirose, K. Narita, M. Sugiyama, Krisana Asano, D. Hu, A. Nakane   +6 more
semanticscholar   +1 more source

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

Biological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito, Judith M. Burkart, Carel van Schaik   +2 more
wiley   +1 more source

Marmosets contain multitudes

eLife
Single-cell RNA sequencing reveals the extent to which marmosets carry genetically distinct cells from their siblings.
Kenneth Chiou, Noah Snyder-Mackler
openaire   +3 more sources

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

Clinical Pharmacology &Therapeutics, EarlyView.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic, Deanne Nixie R. Miao, Britt I. Drögemöller, Alain Dabdoub, Julia M. Abitbol   +4 more
wiley   +1 more source

mRNA expression profile of serotonin receptor subtypes and distribution of serotonergic terminations in marmoset brain [PDF]

, 2014
To better understand serotonin function in the primate brain, we examined the mRNA expression patterns of all the 13 members of the serotonin receptor (5HTR) family, by in situ hybridization and the distribution of serotonergic terminations by serotonin ...
Akiya Watakabe, Rammohan Shukla, Tetsuo Yamamori   +2 more
core   +2 more sources

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

Journal of Infectious Diseases, 2015
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe disease in human with an overall case-fatality rate of >35%. Effective antivirals are crucial for improving the clinical outcome of MERS.
J. Chan, Yanfeng Yao, M. Yeung, Wei Deng, L. Bao, L. Jia, Feng-di Li, C. Xiao, Hong Gao, Pin Yu, Jian-Piao Cai, Hin Chu, Jie Zhou, Honglin Chen, C. Qin, K. Yuen   +15 more
semanticscholar   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

Interdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang, Ling Zhu, Yang Luo   +6 more
wiley   +1 more source

A Common Variant Associated with Dyslexia Reduces Expression of the KIAA0319 Gene [PDF]

, 2009
Numerous genetic association studies have implicated the KIAA0319 gene on human chromosome 6p22 in dyslexia susceptibility. The causative variant(s) remains unknown but may modulate gene expression, given that (1) a dyslexia-associated haplotype has been
Megan Y. Dennis, Silvia Paracchini, Thomas S. Scerri, Ludmila Prokunina-Olsson, Julian C. Knight, Richard Wade-Martins, Penny Coggill, Stephan Beck, Eric D. Green, Anthony P. Monaco, Lisa Stubbs, SE Fisher, SE Shaywitz, SE Shaywitz, JC DeFries, JC DeFries, JM Finucci, JW Gilger, JC DeFries, M Taipale, TS Scerri, KG Wigg, K Hannula-Jouppi, H Meng, J Schumacher, C Francks, N Cope, D Harold, M Luciano, S Paracchini, H Anthoni, AM Galaburda, GD Rosen, SW Threlkeld, Y Wang, TJ Burbridge, S Paracchini, AM Galaburda, AJ Marlow, SE Fisher, GR Abecasis, JC Barrett, S Schwartz, NG Copeland, S Warming, GH Perdew, DC King, J Taylor, JW Thomas, A Visel, WJ Kent, AE Kel, R Kageyama, PI Lin, S Paracchini, JA Fiez, P Swoboda, R Dubruille, M Gotz, KY Chau, JD Klemm, RA Sturm, T Kiyota, MK Kim, J Bode, E Birney, JC Knight, T Pastinen   +67 more
core   +5 more sources

Global distribution and contexts of interactions between humans and non‐human primates: A systematic review

People and Nature, EarlyView.
Abstract Understanding the frequency and socio‐ecological drivers of contacts between humans and non‐human primates (NHPs) is crucial for enhancing coexistence that favours NHP conservation, while limiting negative consequences such as aggressions and cross‐species disease transmission.
Cristina Caparrós‐Vallcorba, Filipe Vieira Santos de Abreu, Claudio Azat, Julio A. Benavides   +3 more
wiley   +1 more source

A MOSAIC of methods: Improving ortholog detection through integration of algorithmic diversity

, 2014
Ortholog detection (OD) is a critical step for comparative genomic analysis of protein-coding sequences. In this paper, we begin with a comprehensive comparison of four popular, methodologically diverse OD methods: MultiParanoid, Blat, Multiz, and OMA ...
Hernandez, Ryan D., Maher, M. Cyrus
core   +2 more sources