Results 101 to 110 of about 8,068 (254)

Acute Myeloid Leukemia—Genetic Alterations and Their Clinical Prognosis

International Journal of Hematology-Oncology and Stem Cell Research, 2016
Acute myeloid leukemia (AML) is a group of hematological diseases, phenotypic and genetically heterogeneous, characterized by abnormal accumulation of blast cells in the bone marrows and peripheral blood.
Francisco Alejandro Lagunas-Rangel, Venice Chávez-Valencia, Miguel Ángel Gómez-Guijosa, Carlos Cortés-Penagos   +3 more
doaj  

A minimal rupture cascade model for living cell plasticity

New Journal of Physics, 2018
Under physiological and pathological conditions, cells experience large forces and deformations that often exceed the linear viscoelastic regime. Here we drive CD34 ^+ cells isolated from healthy and leukemic bone marrows in the highly nonlinear elasto ...
Stefano Polizzi, Bastien Laperrousaz, Francisco J Perez-Reche, Franck E Nicolini, Véronique Maguer Satta, Alain Arneodo, Françoise Argoul   +6 more
doaj   +1 more source

LSD1 expression with Western blotting detection.

, 2013
(A) In tibia bone marrows of bone cancer pain rats at day 14 after MRMT-1 inoculation, MRMT-1 cells cultured for 48 h, MRMT-1 subcutaneous tumors of rats at day 14 after vaccination and breast tissues of normal rats.
Yan Tang (195081), Jia Liu (41593), Hui Li (32376), You Wan (250092), Feng-Yu Liu (389343), Wen Chen (30046), Fei-Fei Liao (389350), Zhi-Qian Tong (389344), Zhi-Hua Li (389345), Wen-Hong Luo (389346), Hong-Jun Luo (389347), Jie Cai (389349), Jun-Min Tang (389348)   +12 more
core   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

Advanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han, Shuvra Mondal, Sungkeun Han, Chan‐Hwi Eom, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +5 more
wiley   +1 more source

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Some Morphological Observation on the Innervation within Bone-Marrows 3rd Chapter On innervation found in the bone-marrow of various mammal's femur (Human, Cows, Cats.) [PDF]

, 1957
I have succeeded to obtain results as follows, by taking examination on the nerve distribution within bone-marrows of human, caw's, and cat's femur.
Tanaka, Motosuke
core  

Histological findings in the bone marrow of irradiated mice.

, 2015
Mice were treated with or without 3 g/kg of ascorbic acid immediately after 8 Gy WBI. Bone marrows were obtained from the ascorbic acid-treated (A, C) or non-treated (B, D) mice 14 days after WBI and were stained with hematoxylin and eosin.
Yasuo Mukai (526702), Masaru Takeuchi (93147), Tetsuo Yamamoto (526701), Shuhji Seki (275998), Masataka Ito (309625), Tomohito Sato (689206), Manabu Kinoshita (156459), Takafumi Nishida (689207), Daizoh Saitoh (689208)   +8 more
core   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source