Results 61 to 70 of about 473,493 (245)

A new generic feline quality of life (FelQoL) questionnaire: part 1 – development and validation

open access: yesJournal of Feline Medicine and Surgery
Objectives The central aim of this study was to develop a questionnaire that can be used to assess the combined emotional and physical wellbeing of pet cats – that is, to evaluate their quality of life (QoL).
Luca Albergante   +9 more
doaj   +1 more source

Investigation of risk factors associated with Ancylostoma spp. infection and the benzimidazole F167Y resistance marker polymorphism in dogs from the United States

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance
Ancylostoma caninum is the most significant intestinal nematode parasite of dogs. We acquired fecal surveillance data from a large population of dogs in the United States (US). A diagnostic test using real-time PCR (qPCR) for Ancylostoma spp.
Pablo D. Jimenez Castro   +7 more
doaj   +1 more source

Cooling of 3D granular gases in microgravity experiments

open access: yesEPJ Web of Conferences, 2017
Granular gases are a most peculiar state, superficially similar to molecular gases: They are loose ensembles of moving grains, rarely interacting with each other and with container walls.
Harth Kirsten   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Immunological detection of small organic molecules in the presence of perchlorates: relevance to the life marker chip and life detection on Mars. [PDF]

open access: yes, 2011
The proposed ExoMars mission, due to launch in 2018, aims to look for evidence of extant and extinct life in martian rocks and regolith. Previous attempts to detect organic molecules of biological or abiotic origin on Mars have been unsuccessful ...
David C. Cullen   +5 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A new generic feline quality of life (FelQoL) questionnaire: part 2 – initial evaluation of clinical utility

open access: yesJournal of Feline Medicine and Surgery
Objectives The aim of this study was to analyse how demographics (breed, age, sex, neutering status), health and the environment (access to environmental features, weather and emotional state of the owner) affect the quality of life (QoL) of cats as ...
Luca Albergante   +9 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Mapping of a Major QTL for Ceratocystis Wilt Disease in an F1 Population of Theobroma cacao

open access: yesFrontiers in Plant Science, 2018
Cacao is an important crop, its beans are key raw materials for the chocolate and cosmetic industries. Ceratocystis wilt of cacao (CWC) caused by Ceratocystis cacaofunesta is a lethal disease for the crop.
Luciel dos Santos Fernandes   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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