Results 191 to 200 of about 140,234 (311)

Strong nickel enrichment co-located with redox-organic interactions in Neretva Vallis, Mars. [PDF]

Nat Commun
Manelski HT, Wiens RC, Broz A, Hurowitz JA, Tice M, Clegg S, Dehouck E, Randazzo N, Connell SA, Forni O, VanBommel SJ, Schröder S, Mandon L, Gabriel TSJ, Bedford CC, Martinez RK, Cloutis EA, Cousin A, Cable ML.   +18 more
europepmc   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Triboelectric Nanogenerators for Future Space Missions. [PDF]

Nanomicro Lett
Shaukat RA, Rehman MM, Khan M, Chang R, Iorio CS, Samad YA, Shi Y.   +6 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Diverse organic molecules on Mars revealed by the first SAM TMAH experiment. [PDF]

Nat Commun
Williams AJ, Eigenbrode JL, Millan M, Williams RH, Mcintosh OM, Teinturier S, Roach J, Malespin C, McAdam AC, Mahaffy P, Bryk AB, Buch A, Boulesteix D, Chou L, Dworkin JP, Fox V, Franz HB, Freissinet C, Glavin DP, House CH, Johnson SS, Lewis JMT, Mojarro A, Navarro-Gonzalez R, Pozarycki C, Steele A, Summons RE, Szopa C, Thorpe MT, Vasavada AR.   +29 more
europepmc   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Democratizing space: India's frugal space innovation provides key lessons for emerging nations. [PDF]

Proc Natl Acad Sci U S A
Corrado L, Gupta-Rawal S, Kattuman P, Prabhu J.   +3 more
europepmc   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Searching for extraterrestrial life advances terrestrial sustainability. [PDF]

Nat Commun
Howells AEG, Fontana CG, Elkassas S, Caro TA, Kashyap S.   +4 more
europepmc   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source