Results 71 to 80 of about 6,477,198 (276)
Calibrating mars orbiter laser altimeter pulse widths at mars science laboratory candidate landing sites [PDF]
, 2014 Accurate estimates of surface roughness allow quantitative comparisons between planetary terrains. These comparisons enable us to improve our understanding of commonly occurring surface processes, and develop a more complete analysis of candidate landing
Muller, J.-P. +6 more
core +1 more source
Low-cost, multi-agent systems for planetary surface exploration [PDF]
, 2012 The use of off-the-shelf consumer electronics combined with top-down design methodologies have made small and inexpensive satellites, such as CubeSats, emerge as viable, low-cost and attractive space-based platforms that enable a range of new and ...
Punzo, Giuliano +4 more
core +3 more sources
Continuity and Change in U.S. Space Exploration Approaches (2017–2025)
Вестник Московского Университета. Серия XXV: Международные отношения и мировая политикаIn recent years, amid the increasing polarization in American society, the United States has witnessed growing divergences between its key parties on virtually all domestic and foreign policy issues. However, this trend has barely affected U.S.
P. G. Koshkin
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mars Exploration Program and Mars Technology Program
, 2002 The Mars Exploration Program and constituent Mars Technology Program are described. Current, ongoing and future NASA-led missions are presented, including discussions of scientific accomplishments and objectives as well as technology validations ...
Whetsel, Charles W.
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Erosion rate and previous extent of interior layered deposits on Mars revealed by obstructed landslides [PDF]
, 2014 We describe interior layered deposits on Mars that have obstructed landslides before undergoing retreat by as much as 2 km. These landslides differ from typical Martian examples in that their toe height increases by as much as 500 m in a distinctive ...
Warner, N.H., Grindrod, Peter M.
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source