Results 61 to 70 of about 6,477,198 (276)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Mars exploration program [PDF]
, 1993 An overview of the Mars Exploration Program is presented in outline and graphic form. Mission objectives, mission strategy, operations concept, transportation element, launch vehicle considerations and program schedule are ...
Weary, Dwayne
core
Mars, The Nearest Habitable World — A Comprehensive Program For Future Mars Exploration [PDF]
Bulletin of the AAS, 2021 Bruce Jakosky +16 more
openaire +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Московский журнал международного праваINTRODUCTION. The study presents a comprehensive analytical review of legal challenges in Mars colonization, examining the evolution and systemic gaps in international space law.
Ya. E. Brazovskaya, D. M. Avdysh
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
ESA's Mars Program: European Plans for Mars Exploration [PDF]
, 2005 A viewgraph presentation on the European Space Agency Mars Exploration Program is shown. The topics include: 1) History:Mars Exploration in Europe; 2) A few preliminary results from Mars Express; 3) A new instrument:Radar MARSIS; and 4) European Mars ...
Forget, Francois
core
Research on main control parameters for LCO2 flash boiling abrasive jet based on ISRU on Mars
Meitan xuebaoSpace exploration and extraterrestrial resource extraction have emerged as comprehensive focal points in both major power strategic competition and the building of a shared future for humanity.
Wenchuan LIU +5 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source