Results 141 to 150 of about 6,505,885 (276)

Mars Exploration Program: Mars for Educators

This National Aeronautics and Space Administration (NASA) site contains links to classroom resources and curriculum supplements relating to the exploration of Mars.

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The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

ibSLS as a biobank for democratizing access to multi-omics data and biospecimens from spaceflight research. [PDF]

Nat Commun
Otsuki A, Aoki Y, Okada R, Baird L, Kamimura D, Shiba D, Hishinuma E, Koshiba S, Katsuoka F, Kinoshita K, Suzuki T, Uruno A, Yamamoto M.   +12 more
europepmc   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Induced magnetosphere of Mars responds fast to interplanetary magnetic field rotation. [PDF]

Nat Commun
Lin R, Zhou J, Huang S, Yuan Z, Wang Y, Wu H, Jiang K, Xu S, Zou Z, Su Z, Zhang T, Dong Y, Xiong Q, Huang H.   +13 more
europepmc   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Emergence of biosignatures on Earth and implications for life detection. [PDF]

Proc Natl Acad Sci U S A
Barge LM, Eigenbrode JL, Fournier G, Theiling B.   +3 more
europepmc   +1 more source

Mars Student Imaging Project (MSIP)

The Mars Student Imaging Project (MSIP) allows students to participate in research, mapping activities, and labs relating to Mars exploration. The program, run by Arizona State University, offers students nationwide the opportunity to conduct authentic ...

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Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

The chemistry of habitable oceans in the Solar system. [PDF]

Nat Commun
Hao J, Zhu Y, Knoll AH, Tosca NJ, He C, Vetter MCYL, Liao L, Crockford PW, Stüeken EE, Huo A, Li J, Mondal JA, Catling DC, Song Y, Ju P, Pan L, Huang F, Glein CR.   +17 more
europepmc   +1 more source