Results 51 to 60 of about 6,477,182 (276)
Towards an integrated scientific and social case for human space exploration [PDF]
I will argue that an ambitious programme of human space exploration, involving a return to the Moon, and eventually human missions to Mars, will add greatly to human knowledge. Gathering such knowledge is the primary aim of science, but science's compart-
Crawford, Ian
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Multi-criteria Overlay Analysis for Identifying Preferred Exploration Zones on Mars
Selecting sites for future human and robotic missions to Mars requires the integration of diverse data sets. A variety of global data sets have been exploited, including geological, mineralogical, and topographical.
Yousef Mashal +3 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Mars Science Laboratory: The Next Rover
This presentation was part of the session : Opening - Thursday Parallel Sessions - June 26Sixth International Planetary Probe WorkshopThe Mars Science Laboratory rover represents firsts in many aspects for interplanetary exploration.
Meyer, Michael D.
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Mars is the terrestrial planet in the solar system that is closest to the Earth. Studying the atmospheric parameters of Mars and studying the evolutionary history of the Martian environment on this basis is helpful for people to discover signs of ...
KeXin Ming +4 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Japanese space programs: Orientation towards the exploration of the bodies of the Solar System
The article discusses Japan’s policy in the field of space program development. The emphasis is on the analysis of scientific projects in the field of space.
T. K. Blokhina +4 more
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Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source

