Results 111 to 120 of about 6,477,182 (276)

Mars Exploration Rovers: 4 Years on Mars [PDF]

, 2008
This January, the Mars Exploration Rovers "Spirit" and "Opportunity" are starting their fifth year of exploring the surface of Mars, well over ten times their nominal 90-day design lifetime.
Landis, Geoffrey A.
core  

The New Horizons Extended Mission Target: Arrokoth Search and Discovery

The Planetary Science Journal
Following the Pluto flyby of the New Horizons spacecraft, the mission provided a unique opportunity to explore the Kuiper Belt in situ. The possibility existed to fly by a Kuiper Belt object (KBO), as well as to observe additional objects at distances ...
Marc W. Buie, John R. Spencer, Simon B. Porter, Susan D. Benecchi, Alex H. Parker, S. Alan Stern, Michael Belton, Richard P. Binzel, David Borncamp, Francesca DeMeo, S. Fabbro, Cesar Fuentes, Hisanori Furusawa, Tetsuharu Fuse, Pamela L. Gay, Stephen Gwyn, Matthew J. Holman, H. Karoji, J. J. Kavelaars, Daisuke Kinoshita, Satoshi Miyazaki, Matt Mountain, Keith S. Noll, David J. Osip, Jean-Marc Petit, Neill I. Reid, Scott S. Sheppard, Mark Showalter, Andrew J. Steffl, Ray E. Sterner, Akito Tajitsu, David J. Tholen, David E. Trilling, Harold A. Weaver, Anne J. Verbiscer, Lawrence H. Wasserman, Takuji Yamashita, Toshifumi Yanagisawa, Fumi Yoshida, Amanda M. Zangari   +39 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Perspectives for Crewed Missions to Mars: Exploration from Orbit and/or Short Stay

The debate “humans versus robots”, on Mars or anywhere else will not be engaged here. The decision has been made—by a single entity, a coalition, or a wide international agreement—to send astronauts to Mars.
Puumala, Mikko, de Vera, Jean Pierre Paul, Sivula, Oskari, Kereszturi, Akos, Milligan, Tony, Ewald, Reinhold, Mason, Nigel, Javaux, Emmanuelle J., Possnig, Carmen, Viso, Michel, Chatzitheodoridis, Elias, Lee, Natuschka M.,, Siljeström, Sandra, De Vera, Jean-Pierre, Javaux, Emmanuelle, Arnould, Jacques, Holynska, Malgorzata, Detrell, Gisela, Freissinet, Caroline, Vago, Jorge L., Mason, N. J., Lehto, Kirsi, Lee, Natuschka M., Lee, Natuschka   +23 more
core   +1 more source

Constraining Near-simultaneous Radio Emission from Short Gamma-Ray Bursts Using CHIME/FRB

The Astrophysical Journal
We use the Canadian Hydrogen Intensity Mapping Experiment (CHIME) Fast Radio Burst (FRB) Project to search for FRBs that are temporally and spatially coincident with gamma-ray bursts (GRBs) occurring between 2018 July 7 and 2023 August 3.
Alice P. Curtin, Sloane Sirota, Victoria M. Kaspi, Shriharsh P. Tendulkar, Mohit Bhardwaj, Amanda M. Cook, Wen-Fai Fong, B. M. Gaensler, Robert A. Main, Kiyoshi W. Masui, Daniele Michilli, Ayush Pandhi, Aaron B. Pearlman, Paul Scholz, Kaitlyn Shin   +14 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Planet Masses, Radii, and Orbits from NASA’s K2 Mission

The Astrophysical Journal Supplement Series
We report the masses, sizes, and orbital properties of 86 planets orbiting 55 stars observed by NASA’s K2 Mission with follow-up Doppler measurements by the HIRES spectrometer at the W. M.
Andrew W. Howard, Evan Sinukoff, Sarah Blunt, Erik A. Petigura, Ian J. M. Crossfield, Howard Isaacson, Molly Kosiarek, Ryan A. Rubenzahl, John M. Brewer, Benjamin J. Fulton, Courtney D. Dressing, Lea A. Hirsch, Heather Knutson, John H. Livingston, Sean M. Mills, Arpita Roy, Lauren M. Weiss, Bjorn Benneke, David R. Ciardi, Jessie L. Christiansen, William D. Cochran, Justin R. Crepp, Erica Gonzales, Brad M. S. Hansen, Kevin Hardegree-Ullman, Steve B. Howell, Sébastien Lépine, Arturo O. Martinez, Leslie A. Rogers, Joshua E. Schlieder, Michael Werner, Alex S. Polanski, Isabel Angelo, Corey Beard, Aida Behmard, Luke G. Bouma, Casey L. Brinkman, Ashley Chontos, Fei Dai, Paul A. Dalba, Steven Giacalone, Samuel K. Grunblatt, Michelle L. Hill, Stephen R. Kane, Jack Lubin, Andrew W. Mayo, Teo Mocnik, Joseph M. Akana Murphy, Malena Rice, Lee J. Rosenthal, Dakotah Tyler, Judah Van Zandt, Samuel W. Yee   +52 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source