Results 181 to 190 of about 80,898 (289)

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Photostability of polycyclic aromatic hydrocarbons in hydrated magnesium sulfate under Martian ultraviolet irradiation to assist organics detection on Mars. [PDF]

Sci Rep
Alberini A, Fornaro T, García-Florentino C, Poggiali G, Biancalani S, Renzi F, Grazioso T, Tasinato N, Jiménez DA, Vicente-Retortillo Á, Becucci M, Cloutis EA, Connell S, Famiglini G, Cappiello A, Martinez GM, Battistuzzi M, Lorenz C, Steele A, Martínez-Frías J, Gómez F, Wiens RC, Hand KP, Brucato JR.   +23 more
europepmc   +1 more source

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park, Emily J. Koubek, Richard Beare, Lynn Ang, Brian C. Callaghan, Rodica Pop‐Busui, Eva L. Feldman, Evan L. Reynolds   +7 more
wiley   +1 more source

Near-surface liquid water on Mars inferred from seasonal marsquakes. [PDF]

Nat Commun
Shi J, Li J, Li C, Meng H, Sun C, Qi C, Pan L, Fan S, Tian Z, Wang T, Xue L, Hu X, Chen L.   +12 more
europepmc   +1 more source

Launch Opportunities and Preliminary Orbit Design for Next Mars Exploration Program

Launch Opportunities and Preliminary Orbit Design for Next Mars Exploration Program
資料番号 ...
openaire  

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

A multi-distance laser-induced breakdown spectroscopy data classification method based on deep convolutional neural network and spectral sample weight optimization. [PDF]

Sci Rep
Zhang X, Li L, Cui Z, Xu W, Xu X, Shu R, Liu X, Wang J.   +7 more
europepmc   +1 more source

Overview of Scientific Objectives of China-Russia Joint Mars Exploration Program YH-1

Chinese Journal of Space Science, 2009
Ji Wu, Guangwu Zhu, Hua Zhao, Chi Wang, Lei Li, Yueqiang Sun, Wei Guo, Chengli Huang   +7 more
openaire   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Validation of self-hearing test in non-clinical setting: a systematic literature review. [PDF]

Braz J Otorhinolaryngol
Mohammed Hatta NH, Wan Mohamad WN, Normani Zakaria M, Nor Rashid MF, Abu Hassan MSN, Hosshan H.   +5 more
europepmc   +1 more source