Results 221 to 230 of about 639,433 (345)

An astrobiological perspective on microbial biofilms: their importance for habitability and production of detectable and lasting biosignatures. [PDF]

Appl Environ Microbiol
Gonzalez-Henao S, Schrenk MO.
europepmc   +1 more source

CircAars‐Engineered ADSCs Facilitate Maxillofacial Bone Defects Repair Via Synergistic Capability of Osteogenic Differentiation, Macrophage Polarization and Angiogenesis

Advanced Healthcare Materials, EarlyView.
Schematic representation of circAars‐engineered‐ADSCs incorporated into GelMA scaffolds for craniomaxillofacial bone regeneration. CircAars‐engineered ADSCs embedded in GelMA scaffolds enhance the repair of critical‐sized bone defects by binding miR‐128‐3p in the cytoplasm, thereby inhibiting its activity.
Yi He, Yunyang Lu, Runze Li, Yuquan Tang, Weidong Du, Lejia Zhang, Jie Wu, Kechen Li, Weijie Zhuang, Shiyu Lv, Yaoling Han, Bailong Tao, Feilong Deng, Wei Zhao, Dongsheng Yu   +14 more
wiley   +1 more source

Highly enriched carbon and oxygen isotopes in carbonate-derived CO₂ at Gale crater, Mars. [PDF]

Proc Natl Acad Sci U S A
Burtt DG, Stern JC, Webster CR, Hofmann AE, Franz HB, Sutter B, Thorpe MT, Kite ES, Eigenbrode JL, Pavlov AA, House CH, Tutolo BM, Des Marais DJ, Rampe EB, McAdam AC, Malespin CA.   +15 more
europepmc   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Special Issue: 'Advances in Space Biology'. [PDF]

Life (Basel)
Pacelli C, Ferranti F, Del Bianco M.
europepmc   +1 more source

Matrix Viscoelasticity Orchestrates Osteogenesis via Mechanotransduction Mediated Metabolic Switch in Macrophages

Advanced Healthcare Materials, EarlyView.
Fast‐relaxation viscoelastic hydrogel triggers a metabolic shift in macrophages, favoring oxidative phosphorylation (OXPHOS) over glycolysis via vasodilator‐stimulated phosphoprotein (VASP) / hypoxia‐inducible factor 1 alpha (HIF1α) signaling meditated mechanotransdution, thereby enhancing their capacity to recruit mesenchymal stem cells (MSCs) and ...
Dihao Tao, Hanzhe Wang, Shiping Chang, Jiayu Cheng, Ningning Da, Li Zhang, Jianhua Yang, Wenzhe Wang, Feng Xu, Bei Li   +9 more
wiley   +1 more source

Water and other volatiles on Mars. [PDF]

Natl Sci Rev
Hu S, Gao Y, Zhou Z, Gao L, Lin Y.
europepmc   +1 more source

Launch Opportunities and Preliminary Orbit Design for Next Mars Exploration Program

Launch Opportunities and Preliminary Orbit Design for Next Mars Exploration Program
資料番号 ...
openaire  

Nano‐Topography Enhanced Topological‐Cell‐Analysis in Radiation‐Therapy

Advanced Healthcare Materials, EarlyView.
Radiotherapy, a treatment that implies exposition of cells to radiation, offers promise to treat cancer. Here, it is hypothesized that the nanoscale details of a scaffold can amplify the response of cells to radiation, measured through topological variables, providing ways to assess the efficacy of Radiotherapy treatment.
Francesca Pagliari, Maria‐Francesca Spadea, Pierre Montay‐Gruel, Anggraeini Puspitasari‐Kokko, Joao Seco, Luca Tirinato, Angelo Accardo, Francesco De Angelis, Francesco Gentile   +8 more
wiley   +1 more source