Results 61 to 70 of about 6,787,265 (281)

Mars, The Nearest Habitable World — A Comprehensive Program For Future Mars Exploration [PDF]

open access: yesBulletin of the AAS, 2021
Bruce Jakosky   +16 more
openaire   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Contemporary Legal Challenges in Mars Colonization: a Comprehensive Analytical Review of Regulatory Frameworks (2024–2025)

open access: yesМосковский журнал международного права
INTRODUCTION. The study presents a comprehensive analytical review of legal challenges in Mars colonization, examining the evolution and systemic gaps in international space law.
Ya. E. Brazovskaya, D. M. Avdysh
doaj   +1 more source

Mars Exploration Program 2007-08 Science Planning, with MEP Requests of MEPAG

open access: yes, 2007
This slide presentation reviews the planning for the Mars Exploration Program. This includes information on the Mars Science Orbiter, the 2016-2018 planning teams, and updates to the Mars Exploration Analysis ...
Meyer, Michael, Beaty, David
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Research on main control parameters for LCO2 flash boiling abrasive jet based on ISRU on Mars

open access: yesMeitan xuebao
Space exploration and extraterrestrial resource extraction have emerged as comprehensive focal points in both major power strategic competition and the building of a shared future for humanity.
Wenchuan LIU   +5 more
doaj   +1 more source

Mars Exploration Program and Mars Technology Program

open access: yes, 2002
The Mars Exploration Program and constituent Mars Technology Program are described. Current, ongoing and future NASA-led missions are presented, including discussions of scientific accomplishments and objectives as well as technology validations ...
Whetsel, Charles W.
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Mars Science Laboratory: The Next Rover

open access: yes, 2008
This presentation was part of the session : Opening - Thursday Parallel Sessions - June 26Sixth International Planetary Probe WorkshopThe Mars Science Laboratory rover represents firsts in many aspects for interplanetary exploration.
Meyer, Michael D.
core   +1 more source

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