Results 181 to 190 of about 1,106,622 (296)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Bio-Inspired Sensitivity-Weighted NSGA-II Optimization of a 6-UPS Parallel Loading Mechanism for Aero-Engine Pylon Vector-Force Loading. [PDF]

Biomimetics (Basel)
Zhang Y, Pan Y, Wang L, Cui H, Jiang S, Ding L, Chen S, Yue Y, Chen B.   +8 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Communication Difficulties and Associations With Health Literacy, Medication Beliefs, and Adherence in Multiple Sclerosis. [PDF]

Brain Behav
Khdair S, Al-Qerem W, Basem D, Eberhardt J, Sawaftah L.   +4 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Detection of Zwan-Wolf effect in the ionosphere of Mars. [PDF]

Nat Commun
Fowler CM, Hanley KG, McFadden J, Mitchell D, Halekas J, Andersson L, Bark D, Ma Y, Chaston C, Sanchez-Cano B, Lester M, Brain D, Mazelle C, Espley J, Benna M, Jolitz R, Ramstad R, Curry S.   +17 more
europepmc   +1 more source

Targeting Mars - The Mars Express science planning and operations [PDF]

, 2005
Pischel, R., Zegers, T., Hoffmann, H., Hauber, E., Mertens, V., Roatsch, T., Jaumann, R., Matz, K.-D., Companys, V., Lauer, M., Denis, M., Moorhouse, A., Rabenau, E., Ricketts, M.   +13 more
openaire   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Evidence of an enhanced near-surface ozone layer at tropical latitudes on Mars. [PDF]

Proc Natl Acad Sci U S A
Viúdez-Moreiras D, Smith MD, Wolff M, Brown MAJ, Daerden F, Zorzano MP, Apestigue V, Arruego I, García E, Jiménez JJ, Toledo D, Lemmon MT, Knutsen EW, Saiz-Lopez A.   +13 more
europepmc   +1 more source

Mars Express radar on hold [PDF]

Nature, 2005
openaire   +1 more source