Results 21 to 30 of about 151,537 (265)

The Na/K-ATPase α1/Src Signaling Axis Regulates Mitochondrial Metabolic Function and Redox Signaling in Human iPSC-Derived Cardiomyocytes

Biomedicines, 2023
Na/K-ATPase (NKA)-mediated regulation of Src kinase, which involves defined amino acid sequences of the NKA α1 polypeptide, has emerged as a novel regulatory mechanism of mitochondrial function in metazoans.
Liquan Cai, Marco T. Pessoa, Yingnyu Gao, Sidney Strause, Moumita Banerjee, Jiang Tian, Zijian Xie, Sandrine V. Pierre   +7 more
doaj   +1 more source

Orthopaedic Surgeon Density in West Virginia

Marshall Journal of Medicine, 2019
West Virginia (WV) has many healthcare disparities and access barriers. For bone and joint disorders, WV has some of the highest rates of musculoskeletal problems, including the highest reported rate of adult arthritis in the nation (36.2%).
Franklin D. Shuler , Grant S. Buchanan , Zachary Sanford, Milad Modarresi , James Timothy Reagan, Kelly Scott, Chad Fisher, Ali Oliashirazi   +7 more
doaj   +1 more source

Outcomes of Transcutaneous Aortic Valve Replacement among high risk WV sample population

Marshall Journal of Medicine, 2018
Introduction:Transcatheter aortic valve replacement (TAVR) is a relatively new strategy for replacing the aortic valve. We elected to review our early experience to see if we could identify clinical characteristics at baseline or immediately following ...
George M. Yousef , Julia Poe, Cameron Killmer , Basel Edris, Jason Mader, Ellen A. Thompson, Daniel Snavely, Silvestre Cansino, Joseph I. Shapiro, Mark A. Studeny   +9 more
doaj   +1 more source

Carbon Monoxide: A Rare Cause of Myocardial Ischemia

Marshall Journal of Medicine, 2019
In an acute care setting, chemical asphyxiants (CA) are a vice which cause debilitating injury. Carbon monoxide (CO) is one well known CA which causes hypoxic injury to cardiovascular and neurological tissue.
Kanaan Mansoor, Greg Parkins, Laurie Wilson, Jerry White , Brandon S. Shiflett , Aman Ajmeri , Fuad Zeid   +6 more
doaj   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

Predicting Adverse Outcomes in Chronic Kidney Disease Using Machine Learning Methods: Data from the Modification of Diet in Renal Disease

Marshall Journal of Medicine, 2017
Background: Understanding factors which predict progression of renal failure is of great interest to clinicians. Objectives: We examined machine learning methods to predict the composite outcome of death, dialysis or doubling of serum creatinine using
Zeid Khitan, Anna P. Shapiro, Preeya T. Shah, Juan R. Sanabria, Prasanna Santhanam, Komal Sodhi , Nader G. Abraham, Joseph I. Shapiro   +7 more
doaj   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Estimating the prevalence and incidence of symptomatic hand OA in the Netherlands using primary care electronic health records.

Arthritis Care &Research, Accepted Article.
Objective This study estimated the incidence and prevalence of symptomatic hand osteoarthritis (OA) in the Dutch population using a validated algorithm that integrates free‐text data from primary care electronic health records (EHRs). Methods This retrospective cohort study used the Integrated Primary Care Information (IPCI) database, including EHRs ...
Onur Kaya, Jacoline van den Driest, Laura Struik, Margreet Kloppenburg, Ruud Selles, Daniel Prieto Alhambra, Sita Bierma‐Zeinstra, Dieuwke Schiphof   +7 more
wiley   +1 more source

Vitamin D Deficiency: "At Risk" Patient Populations and Potential Drug Interactions

Marshall Journal of Medicine, 2016
Vitamin D is known to play an essential role in calcium homeostasis; however, excessive amounts can have harmful effects. Calcium and vitamin D levels are known to be influenced by drug interactions and pathology ranging from of cancer to cardiovascular ...
Dana Lycans, Elias Salloum, Matthew K. Wingate, Thomas Melvin, Grant S. Buchanan, Franklin D. Shuler   +5 more
doaj   +1 more source

Photo‐Degradable Polyester Networks and Multi‐Photon Printed Objects Based on Cyclic Ketene Acetals

Advanced Functional Materials, EarlyView.
The current work introduces a photoreversible polyester network derived from radical ring‐opening polymerization of cyclic ketene acetals. It combines photoreversible cross‐linking with initiator‐free multi‐photon printing. Reversible network formation, tunable mechanical properties, and selective degradation highlight its potential as a versatile ...
Till Meissner, Julian Fanelli, Vinh Xuan Truong, Rob Jones, Jens Gaitzsch, Christopher Barner‐Kowollik   +5 more
wiley   +1 more source