Results 221 to 230 of about 545,909 (315)

Impaired but now diagnosable: Combining analytic frameworks for incorporating symptom weighting in the classification of full‐threshold and subthreshold posttraumatic stress disorder

open access: yesJournal of Traumatic Stress, EarlyView.
Abstract Individuals with subthreshold posttraumatic stress disorder (PTSD) often experience significant impairment yet face barriers to care (e.g., insurance denials and exclusion from clinical trials) due to strict Diagnostic and Statistical Manual of Mental Disorders (DSM)–based diagnostic criteria that rely entirely on symptom counts.
Krithika Prakash   +13 more
wiley   +1 more source

Posterolateral tibial plateau fractures are associated with anterolateral complex injuries of the knee in primary ACL injury

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Posterolateral tibial plateau fractures (PLTFs) have been increasingly studied due to their association with soft tissue injuries around the knee. This prospective study aimed to determine whether the presence of PLTFs is associated with soft tissue injuries around the knee and correlates with an increased preoperative quantitative ...
Lukas Willinger   +5 more
wiley   +1 more source

Ion Activation Methods for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer. [PDF]

open access: yesCell Rep
Fearon AE   +18 more
europepmc   +1 more source

Property Rights Entrepreneurship: The Drive for Product, Asset, and Resource Excludability

open access: yesManagerial and Decision Economics, EarlyView.
ABSTRACT Property rights are foundational to market economies, and entrepreneurial activity depends heavily on the excludability afforded by property rights. Yet, the role of entrepreneurs in shaping the evolution of property rights has been so thoroughly taken for granted that it often vanishes from analyses.
Thomas J. Dean   +2 more
wiley   +1 more source

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