Results 31 to 40 of about 14,036 (215)

The Na/K-ATPase α1/Src Signaling Axis Regulates Mitochondrial Metabolic Function and Redox Signaling in Human iPSC-Derived Cardiomyocytes

Biomedicines, 2023
Na/K-ATPase (NKA)-mediated regulation of Src kinase, which involves defined amino acid sequences of the NKA α1 polypeptide, has emerged as a novel regulatory mechanism of mitochondrial function in metazoans.
Liquan Cai, Marco T. Pessoa, Yingnyu Gao, Sidney Strause, Moumita Banerjee, Jiang Tian, Zijian Xie, Sandrine V. Pierre   +7 more
doaj   +1 more source

Orthopaedic Surgeon Density in West Virginia

Marshall Journal of Medicine, 2019
West Virginia (WV) has many healthcare disparities and access barriers. For bone and joint disorders, WV has some of the highest rates of musculoskeletal problems, including the highest reported rate of adult arthritis in the nation (36.2%).
Franklin D. Shuler , Grant S. Buchanan , Zachary Sanford, Milad Modarresi , James Timothy Reagan, Kelly Scott, Chad Fisher, Ali Oliashirazi   +7 more
doaj   +1 more source

Outcomes of Transcutaneous Aortic Valve Replacement among high risk WV sample population

Marshall Journal of Medicine, 2018
Introduction:Transcatheter aortic valve replacement (TAVR) is a relatively new strategy for replacing the aortic valve. We elected to review our early experience to see if we could identify clinical characteristics at baseline or immediately following ...
George M. Yousef , Julia Poe, Cameron Killmer , Basel Edris, Jason Mader, Ellen A. Thompson, Daniel Snavely, Silvestre Cansino, Joseph I. Shapiro, Mark A. Studeny   +9 more
doaj   +1 more source

Carbon Monoxide: A Rare Cause of Myocardial Ischemia

Marshall Journal of Medicine, 2019
In an acute care setting, chemical asphyxiants (CA) are a vice which cause debilitating injury. Carbon monoxide (CO) is one well known CA which causes hypoxic injury to cardiovascular and neurological tissue.
Kanaan Mansoor, Greg Parkins, Laurie Wilson, Jerry White , Brandon S. Shiflett , Aman Ajmeri , Fuad Zeid   +6 more
doaj   +1 more source

Mapping Childhood Cancer Care Services in Oceania: Methodological Lessons From the SIOP Global Mapping Programme

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The International Paediatric Oncology Society Global Mapping Programme aims to collect data on global paediatric oncology services by continent, with Africa and Latin America completed. This study reports on the methodology and lessons learned for Oceania, a unique continent with resource disparity across countries, multiple small island ...
Trisha Soosay Raj, Christy Noble, Amy Gray, Daniel C. Moreira, Jennifer Lowe, Maite Gorostegui, Gwenda Anga, Andrew Soma, Milena Lay Dos Santos, Siobhan Cross, Erin Luttrell, Michael Sullivan, Julie Cayrol, Julia Challinor, Neil Ranasinghe, Jordana McLoone, Claire E. Wakefield   +16 more
wiley   +1 more source

Predicting Adverse Outcomes in Chronic Kidney Disease Using Machine Learning Methods: Data from the Modification of Diet in Renal Disease

Marshall Journal of Medicine, 2017
Background: Understanding factors which predict progression of renal failure is of great interest to clinicians. Objectives: We examined machine learning methods to predict the composite outcome of death, dialysis or doubling of serum creatinine using
Zeid Khitan, Anna P. Shapiro, Preeya T. Shah, Juan R. Sanabria, Prasanna Santhanam, Komal Sodhi , Nader G. Abraham, Joseph I. Shapiro   +7 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Trauma Team Activation for Geriatric Trauma at a Level II Trauma Center: Are the Elderly Under-triaged?

Marshall Journal of Medicine, 2017
Geriatric patients often sustain life-threatening injuries from minor trauma. A growing body of research suggests that these patients are often under-triaged in the emergency setting.The purpose of this research was to evaluate whether or not geriatric ...
Grant S. Buchanan, Daniel Scott Kahn, Harry Burke, Brian Czarkowski , Richard Boe , Milad Modarresi , Franklin D. Shuler   +6 more
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source

Mechanisms of Degradation in Li‐Ion Batteries Under Low Temperature Exposures

Advanced Functional Materials, EarlyView.
Low‐temperature exposures, or freeze‐thaw cycles, are observed to significantly accelerate the degradation of Li‐ion batteries. A combination of electrolyte phase separation and mechanochemical stress leads to reversible and irreversible performance losses.
Mihir Ojha, Shervin Alaei, Jayanth Ramamurthy, Luke P. Lounsbury, Md Mahdi Ul Ishtiaque, Stuart Leland, Niraj P. Atale, Sourav Das, Siddhartha Pathak, Pranav Shrotriya, Steve W. Martin, Todd A. Kingston, Cary L. Pint   +12 more
wiley   +1 more source