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Predicting Marshall Flow and Marshall Stability of Asphalt Pavements Using Multi Expression Programming [PDF]

open access: yesBuildings, 2022
The traditional method to obtain optimum bitumen content and the relevant parameters of asphalt pavements entails time-consuming, complicated and expensive laboratory procedures and requires skilled personnel.
Hamad Hassan Awan   +7 more
doaj   +2 more sources

Concrete Asphalt Marshall Stability Using Concrete Objective Waste

open access: yesThe Spirit of Society Journal: International Journal of Society Development and Engagement, 2020
The road is one of the most important infrastructures. The community needs it because the road functions to connect the source of production. Asphalt is an aggregate binding material in road pavement construction, which plays an important role in ...
Sumargono Sumargono   +5 more
doaj   +3 more sources

The Post-Translational Role of UFMylation in Physiology and Disease

open access: yesCells, 2023
Ubiquitin-fold modifier 1 (UFM1) is a newly identified ubiquitin-like protein that has been conserved during the evolution of multicellular organisms.
Xingde Wang, Xingzhi Xu, Zhifeng Wang
doaj   +1 more source

Prediction of Marshall Stability and Marshall Flow of Asphalt Pavements Using Supervised Machine Learning Algorithms

open access: yesSymmetry, 2022
The conventional method for determining the Marshall Stability (MS) and Marshall Flow (MF) of asphalt pavements entails laborious, time-consuming, and expensive laboratory procedures. In order to develop new and advanced prediction models for MS and MF of asphalt pavements the current study applied three soft computing techniques: Artificial Neural ...
Muhammad Aniq Gul   +6 more
openaire   +1 more source

Protocol to purify the histone deacetylase SIRT6 and assess its activity in vitro

open access: yesSTAR Protocols, 2023
Summary: The histone deacetylase known as sirtuin 6 (SIRT6) deacetylates both histone and non-histone proteins but has low deacetylase activity in vitro.
Yuan Tian   +3 more
doaj   +1 more source

Post-Translational Modifications by Lipid Metabolites during the DNA Damage Response and Their Role in Cancer

open access: yesBiomolecules, 2022
Genomic DNA damage occurs as an inevitable consequence of exposure to harmful exogenous and endogenous agents. Therefore, the effective sensing and repair of DNA damage are essential for maintaining genomic stability and cellular homeostasis ...
Guangrong Zhu   +3 more
doaj   +1 more source

The neurological and non-neurological roles of the primary microcephaly-associated protein ASPM

open access: yesFrontiers in Neuroscience, 2023
Primary microcephaly (MCPH), is a neurological disorder characterized by small brain size that results in numerous developmental problems, including intellectual disability, motor and speech delays, and seizures.
Xingxuan Wu   +7 more
doaj   +1 more source

RBM14 promotes DNA end resection during homologous recombination repair

open access: yesActa Biochimica et Biophysica Sinica, 2023
DNA double-strand break (DSB) repair by homologous recombination (HR) is crucial for the maintenance of genome stability and integrity.
Li Zheng   +5 more
doaj   +1 more source

Biogenesis of Iron–Sulfur Clusters and Their Role in DNA Metabolism

open access: yesFrontiers in Cell and Developmental Biology, 2021
Iron–sulfur (Fe/S) clusters (ISCs) are redox-active protein cofactors that their synthesis, transfer, and insertion into target proteins require many components. Mitochondrial ISC assembly is the foundation of all cellular ISCs in eukaryotic cells.
Ruifeng Shi   +6 more
doaj   +1 more source

ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability

open access: yesiScience, 2021
Summary: DNA double-strand break (DSB) repair by homologous recombination (HR) is essential for ensuring genome stability. Abnormal spindle-like microcephaly-associated (ASPM) gene encodes a spindle protein that is commonly implicated in primary ...
Shibin Xu   +5 more
doaj   +1 more source

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