Results 241 to 250 of about 128,514 (315)

A balance between stability and flexibility: Adaptive patterns of self‐regulated learning processes shape game‐based learning

British Journal of Educational Technology, EarlyView.
Abstract To ensure learning efficiency in game‐based learning (GBL), learners must regulate cognitive, affective, metacognitive and motivational (CAMM) processes, collectively known as self‐regulated learning (SRL). SRL is dynamic and non‐linear, characterized by regulatory patterns and CAMM interactions that lead to macro‐level SRL behaviours. In this
Elizabeth B. Cloude, Stefan E. Huber, Jingwei Wei, Bianca Esmanhoto, Muhterem Dindar, Manuel Ninaus, Kristian Kiili   +6 more
wiley   +1 more source

Serotonin engages divergent 5‐HT receptor pathways for cell type‐resolved modulation of prefrontal layer 5 microcircuits

British Journal of Pharmacology, EarlyView.
Serotonin differentially modulates layer 5 mPFC microcircuits through cell type‐specific pre‐ and postsynaptic receptor pathways. Presynaptic 5‐HT1BRs suppress glutamate and GABA release, whereas presynaptic and postsynaptic 5‐HT3ARs enhance fast‐spiking interneuron activity, whilst distinct pyramidal neuron subtypes exhibit divergent 5‐HT1AR‐ and 5 ...
Ramya Rama, Guanxiao Qi, Gabriele Radnikow, Danqing Yang, Dirk Feldmeyer   +4 more
wiley   +1 more source

Regulation of chemicals demands assessment of risks rather than identification of hazards only. [PDF]

Arch Toxicol
Marx-Stoelting P, Ritz V, Herzler M, Kneuer C, Aiello-Holden K, Brescia S, Escher SE, Feustel S, Fritsche E, Gebel J, Kenny EF, Landsiedel R, Sanders P, Schwarz M, Streitz M, Testai E, van Ravenzwaay B, Waetjen W, Wend K, Wilks M, Luch A, Tralau T, Hensel A.   +22 more
europepmc   +1 more source

Virtual cell construction for artificial intelligence‐driven drug discovery

British Journal of Pharmacology, EarlyView.
Cells are the fundamental units through which genetic variation and pharmacological perturbations influence disease processes and therapeutic responses. However, cellular responses to intervention are strongly shaped by biological context, creating a central challenge for drug discovery: predicting how specific perturbations reshape cellular systems ...
Yuran Jia, Xiao Xing, Haoyang Han, Yuansong Zhao, Shiyao Zhou, Jingjing Chen   +5 more
wiley   +1 more source

Understanding Privatisation of Mental Health Services: Insights From Karl Marx's Capital. [PDF]

J Psychiatr Ment Health Nurs
Balfe M.
europepmc   +1 more source

Entrepreneurial State as a Creative Destroyer: Comparison of Hong Kong and Singapore's Creative Industries

Creativity and Innovation Management, EarlyView.
ABSTRACT This paper explores the limits of mission‐directed entrepreneurial states by drawing on the theory of recombinant innovation and F.A. Hayek's insights on the spontaneous growth of knowledge in society. First, the use of discretionary policymaking curtails the range of knowledge generated in the process of social interaction, limiting the scope
Bryan Cheang, Praharsh Mehrotra
wiley   +1 more source

AMRrounds: What goes around comes back around-recurrent KPC-producing <i>Salmonella</i> bacteraemia. [PDF]

JAC Antimicrob Resist
Marx AH, Dial CN, Footer B.
europepmc   +1 more source

How Cardiac Output May be Described in Fontan Patients: An Approximative Equation. [PDF]

Interdiscip Cardiovasc Thorac Surg
Marx M, Albinni S, Kitzmüller E, Michel-Behnke I.   +3 more
europepmc   +1 more source

The Meaning of Cleaning: Conflicting Norms About Learning to Clean in an Era of Outsourcing Domestic Work

Children &Society, EarlyView.
ABSTRACT The aim of this article is to analyse how Swedish mothers, regularly outsourcing cleaning, make use of different discursive resources and negotiate conflicting norms about domestic work when they discuss the role of cleaning in the socialisation of their children.
Ulrika Widding, Ann‐Louise Silfver
wiley   +1 more source