Results 31 to 40 of about 3,274,872 (304)

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Blathmac i jego "Poemat" poświęcony Dziewicy Maryi

open access: yesVox Patrum, 2004
The author presents the poem on the Virgin Mary, the oldest in Ireland and one of the oldest in the Early Medieval Europe. This poem wrote Irish monk of the monastery on Iona, Blathmac (+ 825).
Anna Szewczyk
doaj   +1 more source

PANEL DISCUSSION: THE FEDERAL PROSECUTOR\u27S ROLE IN THE REGULATORY PROCESS [PDF]

open access: yes, 1999
MODERATOR: CharlesM. Carberry PANELISTS: Honorable John S. Martin, Jr., Robert B. Fiske, Jr., Mary Ellen Krist, Ronald K. Noble, Honorable Jed S.

core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Volume 9, Issue 4: Full Issue [PDF]

open access: yes, 2014
Full issue of the May 1942 issue of Manuscripts. Includes work by:Helen Elizabeth Hughes, Jack DeVine, Esther Benjamin, Joe Berry, J. Robert Dietz, Glenn H.

core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The Spirit and Holy Spirit in The Quran and its Exegeses

open access: yesKader
The term ‘Holy Spirit’ is referenced four times in the Quran, with three instances directly related to Jesus Christ, while the broader term ‘spirit’ or “the spirit” (al-Rūḥ) appears eighteen times, some of which pertain to Mary, the mother of Jesus. This
Mohammad Makdod
doaj   +1 more source

Frankenstein: a monstrous romanticism [PDF]

open access: yes, 2010
Includes bibliographical references.The purpose of this thesis is to examine the relationship between Mary Shelley's first novel Frankenstein and her own understanding of Romanticism.
Königkrämer, Lobke
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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